Nebivolol in the management of essential hypertension: a review

W McNeely, KL Goa - Drugs, 1999 - Springer
Nebivolol is a lipophilic β 1-blocker. It is devoid of intrinsic sympathomimetic or membrane
stabilising activity but appears to have nitric oxide-mediated vasodilatory effects. Nebivolol is …

A Randomized, Double‐Blind, Placebo‐Controlled Parallel‐Group Study to Assess the Efficacy and Safety of Nebivolol, a Novel β‐Blocker, in Patients With Mild to …

RJ Weiss, MA Weber, AA Carr… - The Journal of Clinical …, 2007 - Wiley Online Library
This double‐blind, multicenter, randomized placebo‐controlled study evaluated the
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …

Nebivolol: A third-generation β-blocker for hypertension

JWM Cheng - Clinical therapeutics, 2009 - Elsevier
Background: Nebivolol is a third-generation β1-selective β-blocker that is approved for the
treatment of hypertension. Objective: This article reviews the clinical pharmacology of …

Nebivolol vs atenolol and placebo in essential hypertension: a double-blind randomised trial

L Van Nueten, FR Taylor, JIS Robertson - Journal of human …, 1998 - nature.com
A double-blind, randomised, parallel-group trial was conducted in patients with essential
hypertension in British general practices, of nebivolol 5 mg, atenolol 50 mg, and placebo …

Nebivolol: new therapy update

SS Sule, W Frishman - Cardiology in review, 2006 - journals.lww.com
Nebivolol is a β-blocker under US Food and Drug Administration review for the treatment of
hypertension. The unique pharmacologic properties of nebivolol include high specificity for …

Nebivolol versus nifedipine in the treatment of essential hypertension: a double-blind, randomized, comparative trial

L Van Nueten, Y Lacourciere, G Vyssoulis… - American journal of …, 1998 - journals.lww.com
The efficacy and acceptability of 5 mg nebivolol once daily, a long-acting, vasodilating
cardioselective [beta] blocker that additionally facilitates the L-arginine/nitric oxide system …

Efficacy and tolerability profile of Nebivolol vs Atenolol in mild‐to‐moderate essential hypertension: Results of a double‐blind randomized multicentre trial

G Grassi, FQ Trevano, A Facchini, T Toutouzas… - Blood …, 2003 - Taylor & Francis
The objective of this 12‐week double‐blind randomized multicentre study was to compare
the efficacy and tolerability of nebivolol, a recently developed beta‐blocking agent with …

Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis

LM Van Bortel, F Fici, F Mascagni - American Journal of Cardiovascular …, 2008 - Springer
Background and objective Lowering BP to normal levels without quality of life deterioration
is the most important means of reducing cardiovascular risk. Recent studies have …

Nationwide efficacy-safety study of nebivolol in mildly hypertensive patients

TJ Cleophas, R Agrawal, A Lichtenthal… - American journal of …, 2006 - journals.lww.com
Nebivolol has been adequately tested in clinical efficacy trials of patients with mild
hypertension. Clinical efficacy trials or their metaanalyses did not accurately predict the …

Nebivolol: a review of its clinical and pharmacological characteristics.

W Gielen, TJ Cleophas… - International Journal of …, 2006 - search.ebscohost.com
Nebivolol is a cardioselective lipophilic β-blocker devoid of intrinsic sympathomimetic and
membrane-stabilizing actions. The pharmacological profile differs from that of conventional …