A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

Diagnostic chimerism analysis after allogeneic stem cell transplantation: new methods and markers

C Thiede - American Journal of Pharmacogenomics, 2004 - Springer
Abstract Analysis of chimerism after allogeneic hematopoietic cell transplantation is
important for assessing engraftment and the early detection of graft failure. In addition, the …

A novel rapid single nucleotide polymorphism (SNP)–based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation

EP Hochberg, DB Miklos, D Neuberg… - Blood, The Journal …, 2003 - ashpublications.org
A major end point of nonmyeloablative hematopoietic stem cell transplantation is the
attainment of either mixed chimerism or full donor hematopoiesis. Because the majority of …

Recent advances in quantitative chimerism analysis

E Gineikiene, M Stoskus… - Expert review of molecular …, 2009 - Taylor & Francis
Quantitative chimerism analysis is a diagnostic tool used to monitor engraftment kinetics
after allogeneic stem cell transplantation. It reflects the proportion of recipient and donor …

Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) …

JR Clark, SD Scott, AL Jack, H Lee… - British journal of …, 2015 - Wiley Online Library
Analysis of short tandem repeats (STR) is the predominant method for post‐transplant
monitoring of donor engraftment. It can enable early detection of disease relapse, level of …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation: recommendations from a workshop at the 2001 Tandem …

JH Antin, R Childs, AH Filipovich, S Giralt… - Biology of Blood and …, 2001 - tctjournal.org
Approaches to the measurement of lymphohematopoietic chimerism have evolved from
laboratory research to important clinical tools. However, there has been no logical …

Strategies and clinical implications of chimerism diagnostics after allogeneic hematopoietic stem cell transplantation

C Thiede, M Bornhäuser, G Ehninger - Acta haematologica, 2004 - karger.com
Abstract Analysis of donor chimerism has become a routine method for the documentation of
engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years …

New methods for the quantification of mixed chimerism in transplantation

C Picard, C Frassati, N Cherouat, S Maioli… - Frontiers in …, 2023 - frontiersin.org
Background Quantification of chimerism showing the proportion of the donor in a recipient is
essential for the follow-up of hematopoietic stem cell transplantation but can also be useful …

[HTML][HTML] Evaluation of next-generation sequencing and crystal digital PCR for chimerism monitoring of post-allogeneic hematopoietic stem cell transplantation

P Pedini, N Cherouat, A Basire, S Simon… - … and Cellular Therapy, 2021 - Elsevier
Hematopoietic stem cell transplantation (HSCT) is a curative treatment for most hematologic
diseases. To evaluate the level of donor engraftment, chimerism must be carefully monitored …