Lymph nodes (LNs) are strategically positioned at dedicated sites throughout the body to
facilitate rapid and efficient immunity. Central to the structural integrity and framework of LNs …

The initiation of adaptive immune responses depends upon the careful maneuvering of
lymphocytes and antigen into and within strategically placed lymph nodes (LNs). Non …

Lymph node stromal cells (LNSCs) closely regulate immunity and self-tolerance, yet key
aspects of their biology remain poorly elucidated. Here, comparative transcriptomic analyses …

Lymph node stromal cells coordinate the adaptive immune response in secondary lymphoid
organs, providing both a structural matrix and soluble factors that regulate survival and …

A defining characteristic of the immune system is the constant movement of many of its
constituent cells through the secondary lymphoid tissues, mainly the spleen and lymph …

Within lymph nodes, non-hematopoietic stromal cells organize and interact with leukocytes
in an immunologically important manner. In addition to organizing T and B cell segregation …

Secondary lymphoid organs (SLO s), including lymph nodes, P eyer's patches, and the
spleen, have evolved to bring cells of the immune system together. In these collaborative …

Lymph nodes (LNs) are at the cross roads of immunity and tolerance. These tissues are
compartmentalized into specialized niche areas by lymph node stromal cells (LN SCs). LN …

Stromal cells have for a long time been viewed as structural cells that support distinct
compartments within lymphoid tissues and little more. Instead, an active cross-talk between …

Inflammation is an unstable state. It either resolves or persists. Why inflammation persists
and the factors that define tissue tropism remain obscure. Increasing evidence suggests that …