Cardiovascular disease is the number one cause of morbidity and mortality in the United
States, and the prevalence of this disease has been increasing since 2015. 1 Poor patient …

A recent issue of JAMA contains the latest US Preventive Services Task Force (USPSTF)
recommendation statement on statins for prevention of cardiovascular disease in adults, 1 …

Cardiovascular disease is the most common cause of death in the United States and
worldwide. Most of this disease is preventable with improvement of lifestyle and medication …

In this issue of The American Journal of Medicine, Hennekens et al 1 address many cogent
methodologic issues concerning whether there is a valid statistical association between …

The role of low-density lipoprotein cholesterol (LDL-C) in the pathophysiology of
atherosclerosis and coronary artery disease has been well documented. 1 The use of 3 …

Statins (HMG-CoA reductase inhibitors) are one of the most widely prescribed medications
in the world. However, their use in patients is often inappropriate because these medications …

In women and men, cardiovascular disease is and will remain the leading avoidable cause
of premature death in the United States and is rapidly becoming so worldwide. 1 Although …

In this issue, Yebyo and colleagues challenge the risk thresholds in current guidelines for
use of statins for primary prevention of cardiovascular disease. The editorialists discuss how …

Although the primary prevention of atherosclerotic disease events by the use of statins is
both widely promoted and commonly prescribed, Mills et al.(1) astutely note that the clinical …

Cholesterol-lowering statin drugs have become the mainstay of many cholesterol guidelines
and are intended to reduce the risk of atherosclerotic cardiovascular disease and death. In …