Ventricular remodeling in heart failure

MA Gaballa, S Goldman - Journal of cardiac failure, 2002 - Elsevier
This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Cardiac remodeling as a consequence and cause of progressive heart failure

K Kurrelmeyer, D Kalra, B Bozkurt, F Wang… - Clinical …, 1998 - Wiley Online Library
Natural history studies in heart failure have shown that increases in left ventricular (LV)
volume and LV mass are directly related to future deterioration in LV performance and a less …

Relation between left ventricular remodeling and clinical outcomes in heart failure patients with left ventricular systolic dysfunction

JE Udelson, MA Konstam - Journal of cardiac failure, 2002 - Elsevier
Background: A major advance in understanding the pathophysiology of the heart failure
syndrome has been an understanding of the process of left ventricular (LV) remodeling. After …

Postinfarction left ventricular remodeling: a pathophysiological and therapeutic review

Z Yousef, SR Redwood, MS Marber - Cardiovascular drugs and therapy, 2000 - Springer
Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction
have resulted in many potential therapeutic targets being identified and novel classes of …

Mechanisms of postinfarct left ventricular remodeling

BA French, CM Kramer - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Potential novel pharmacological therapies for myocardial remodelling

U Landmesser, KC Wollert, H Drexler - Cardiovascular research, 2009 - academic.oup.com
Left ventricular (LV) remodelling remains an important treatment target in patients after
myocardial infarction (MI) and chronic heart failure (CHF). Accumulating evidence has …

Left ventricular remodeling: pathophysiology and treatment.

N Sharpe - Heart Failure Monitor, 2003 - europepmc.org
Left ventricular (LV) remodeling, which can result from myocardial damage or ventricular
pressure or volume overload, has genomic, cellular, and interstitial components with …

Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies

H Takano, H Hasegawa, T Nagai, I Komuro - Internal Medicine, 2003 - jstage.jst.go.jp
Theconcept and clinical implication of left ventricular remodeling have been gradually
extended. Cardiac re-modeling plays important roles in the progression of car-diovascular …

Drugs for left ventricular remodeling in heart failure

M Frigerio, E Roubina - The American journal of cardiology, 2005 - Elsevier
Left ventricular (LV) remodeling (ie, enlargement and functional deterioration occurring over
time) is among the main mechanisms of progression in heart failure (HF). LV dilatation and …

New concepts in post-infarction ventricular remodeling.

JE Udelson, RD Patten, MA Konstam - Reviews in cardiovascular …, 2003 - europepmc.org
An understanding of the process of left ventricular (LV) remodeling has led to greater
knowledge of the pathophysiology of heart failure syndrome. This article examines the …