Objective: Although lower brain volume has been routinely observed in individuals with
substance dependence compared with nondependent control subjects, the brain regions …

There is quite a body of work assessing functional brain changes in chronic substance
abuse, much less is known about structural brain abnormalities in this patient population. In …

Long-term cocaine consumption is associated with brain structural and functional changes.
While the animal literature on cocaine use and dependence has traditionally focused on the …

Background Schizophrenia and alcoholism are characterized by brain volume
abnormalities. Despite the frequent comorbidity of these conditions, the potentially …

Background: Alcohol abuse has detrimental effects on cerebral function, metabolism, and
volume. Some of these effects were found to be at least partially reversible with continued …

BACKGROUND: Group differences in brain structure between methamphetamine-
dependent and healthy research participants have been reported, but findings in the …

Objective: Alcoholism is associated with gray matter volume deficits in frontal and other brain
regions. Whether persistent brain volume deficits in abstinence are predictive of subsequent …

Background Widespread brain atrophy in alcohol‐dependent individuals (ALC) has been
consistently documented in pathological and magnetic resonance imaging (MRI) studies …

Reduced right amygdala volumes have been reported in young, alcohol‐naïve subjects at
high risk (HR) for alcohol dependence. The differences in brain morphometry have been …

The goals of this study were to measure if chronic active heavy drinking is associated with
brain volume loss in non-treatment seeking men and women, and to assess the effect of …