Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and …

AM Crane, W Feuer, ER Felix, RC Levitt… - British Journal of …, 2017 - bjo.bmj.com
Objective To evaluate how closely neuropathic-like ocular pain (NOP) symptoms align with a
metric of central sensitisation (ie, the presence of persistent ocular pain after topical …

Dry eye symptom severity and persistence are associated with symptoms of neuropathic pain

A Galor, L Zlotcavitch, SD Walter, ER Felix… - British journal of …, 2015 - bjo.bmj.com
Objective Studies of patients with non-ocular pain suggest that it is therapeutically useful to
identify those with features of neuropathic pain. No data is available, however, on whether …

Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye)

M Farhangi, W Feuer, A Galor, D Bouhassira, RC Levitt… - Pain, 2019 - journals.lww.com
Chronic eye pain, which has previously been assumed to be due to ocular surface
abnormalities (ie,“dry eye [DE] disease”), has recently garnered attention as a potential …

[HTML][HTML] Neuropathic ocular pain: an important yet underevaluated feature of dry eye

A Galor, RC Levitt, ER Felix, ER Martin… - Eye, 2015 - nature.com
Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

Patients with more severe symptoms of neuropathic ocular pain report more frequent and severe chronic overlapping pain conditions and psychiatric disease

AM Crane, RC Levitt, ER Felix… - British Journal of …, 2017 - bjo.bmj.com
Objective To study chronic pain and mental health profiles in patients with dry eye (DE)
symptoms, comparing those with high and low levels of neuropathic ocular pain (NOP) …

Neuropathic corneal pain and dry eye: a continuum of nociception

G Dieckmann, D Borsook, E Moulton - British Journal of …, 2022 - bjo.bmj.com
Throughout the body, damage to peripheral nerves normally involved in nociception may
produce a constellation of symptoms—including irritation, itchiness and pain. The …

Neuropathic-like ocular pain and nonocular comorbidities correlate with dry eye symptoms

VS Chang, TP Rose, CL Karp, RC Levitt… - Eye & contact …, 2018 - journals.lww.com
Objective: To evaluate the association between dry eye (DE) symptoms and neuropathic-like
ocular pain (NOP) features, chronic pain conditions, depression, and anxiety in patients …

Assessment of somatosensory function in patients with idiopathic dry eye symptoms

A Galor, RC Levitt, KT McManus… - JAMA …, 2016 - jamanetwork.com
Importance Somatosensory dysfunction likely underlies dry eye (DE) symptoms in many
individuals yet remains an understudied component of the disease. Its presence has …

[HTML][HTML] Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study

A Vázquez, E Martínez-Plaza, I Fernández, EM Sobas… - The Ocular Surface, 2022 - Elsevier
Purpose To describe the clinical characteristics of patients suffering from chronic dry eye
(DE) and pain after refractive surgery (RS). Methods Cross-sectional, observational, single …

[PDF][PDF] Corneal nerve pathway function in individuals with dry eye symptoms

A Galor, ER Felix, W Feuer, RC Levitt… - Ophthalmology, 2021 - Elsevier
Dry eye (DE) disease is a multifactorial, chronic condition with a prevalence of 5-41 30%. 1
DE symptoms are a frequent presenting complaint to eye clinics and can include 42 …