Risk factors for the development of local recurrence in extremity soft-tissue sarcoma

F Tirotta, R Sayyed, RL Jones… - Expert Review of …, 2022 - Taylor & Francis
Introduction Local recurrence (LR) is one of the main pitfalls in surgery for extremities soft
tissue sarcoma (eSTS). Achieving clear histopathological margins is the most important …

Predictors and clinical significance of local recurrence in extremity soft tissue sarcoma

VK Alamanda, SN Crosby, KR Archer, Y Song… - Acta …, 2013 - Taylor & Francis
Background. Limb salvage surgery (LSS) has gained widespread acceptance as the current
treatment for treating extremity soft tissue sarcoma (STS) and has been greatly refined since …

Preoperative therapy for extremity soft tissue sarcomas

LE Davis, CW Ryan - Current treatment options in oncology, 2015 - Springer
Opinion statement High-risk soft tissue sarcomas (STS) are defined as large (> 5 cm),
intermediate/high-grade tumors and can carry a> 50% risk of death from metastases. A …

Selection of patients with localized extremity soft tissue sarcoma for treatment with perioperative chemotherapy

J Charlson - Current Treatment Options in Oncology, 2018 - Springer
Opinion statement Soft tissue sarcoma (STS) is a heterogeneous disease, in terms of
histologic subtype, body site of presentation, and behavior. Localized soft tissue sarcoma …

Quality of surgical margins and local recurrence in primary extremity soft tissue sarcoma (STS).

S Bonvalot, A Dunant, C Le Pechoux… - Journal of Clinical …, 2010 - ascopubs.org
10068 Background: In previous studies, quality of margins after resection of primary STS of
extremity was only defined by their size. Methods: We analyzed all patients (pts) with primary …

[HTML][HTML] Oncological outcome and prognostic factors in the therapy of soft tissue sarcoma of the extremities

I Ingmar, W Tobias, K Beate, K Torsten - Orthopedic Reviews, 2012 - ncbi.nlm.nih.gov
Uniform conclusions about therapeutic concepts and survival time of bone and soft tissue
sarcoma patients are difficult due to the heterogeneity of histological subtypes as well as the …

Soft tissue sarcoma of extremities: the prognostic significance of adequate surgical margins in primary operation and reoperation after recurrence

CY Liu, CC Yen, WM Chen, TH Chen… - Annals of surgical …, 2010 - Springer
Background Adult soft tissue sarcomas (STS) of extremities are prone to recurrence despite
apparently complete resection. This study aimed to explore the impact of clinicopathological …

Impact of resection margin on outcome in soft-tissue sarcomas of the extremities treated with limb-sparing surgery and postoperative radiotherapy

CC Chen, YY Wu, JT Kao, CH Chang… - World Journal of …, 2024 - Springer
Background The standard curative treatments for extremity soft tissue sarcoma (ESTS)
include surgical resection with negative margins and perioperative radiotherapy. However …

[PDF][PDF] Perioperative management of extremity soft tissue sarcomas

RL Haas, A Gronchi, MAJ van de Sande, EH Baldini… - J Clin Oncol, 2018 - academia.edu
Surgery is potentially curative for primary nonmetastatic extremity soft tissue sarcomas. After
surgery alone, patients may remain at risk for local recurrences and/or metastatic disease …

Surgical margins in soft tissue sarcoma of the extremities

HU Steinau, L Steinsträsser, S Langer, I Stricker… - Der …, 2011 - europepmc.org
Negative surgical margins (R0 resection) play a key role in the prevention of local
recurrences of soft tissue sarcoma of the extremities in the multimodal therapy concept. The …