From tea to treatment; epigallocatechin gallate and its potential involvement in minimizing the metabolic changes in cancer

AL Tauber, SS Schweiker, SM Levonis - Nutrition Research, 2020 - Elsevier
As the most abundant bioactive polyphenol in green tea, epigallocatechin gallate (EGCG) is
a promising natural product that should be used in the discovery and development of …

Preclinical activities of epigallocatechin gallate in signaling pathways in cancer

M Sharifi-Rad, R Pezzani, M Redaelli, M Zorzan… - Molecules, 2020 - mdpi.com
Epigallocatechin gallate (EGCG) is the main bioactive component of catechins
predominantly present in various types of tea. EGCG is well known for a wide spectrum of …

[HTML][HTML] Targeting cancer hallmarks with epigallocatechin gallate (EGCG): mechanistic basis and therapeutic targets

WH Talib, D Awajan, A Alqudah, R Alsawwaf… - Molecules, 2024 - mdpi.com
Epigallocatechin gallate (EGCG) is a catechin, which is a type of flavonoid found in high
concentrations in green tea. EGCG has been studied extensively for its potential health …

Potential therapeutic targets of epigallocatechin gallate (EGCG), the most abundant catechin in green tea, and its role in the therapy of various types of cancer

SA Almatroodi, A Almatroudi, AA Khan, FA Alhumaydhi… - Molecules, 2020 - mdpi.com
Epigallocatechin-3-gallate (EGCG), an active compound of green tea and its role in
diseases cure and prevention has been proven. Its role in diseases management can be …

Targeting multiple signaling pathways by green tea polyphenol (−)-epigallocatechin-3-gallate

N Khan, F Afaq, M Saleem, N Ahmad, H Mukhtar - Cancer research, 2006 - AACR
Cell signaling pathways, responsible for maintaining a balance between cell proliferation
and death, have emerged as rational targets for the management of cancer. Emerging data …

Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications

BN Singh, S Shankar, RK Srivastava - Biochemical pharmacology, 2011 - Elsevier
An expanding body of preclinical evidence suggests EGCG, the major catechin found in
green tea (Camellia sinensis), has the potential to impact a variety of human diseases …

Novel mechanisms of anticancer activities of green tea component epigallocatechin-3-gallate

L Zhang, Y Wei, J Zhang - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
After water, tea is the most widely consumed beverage. The major active constituents in
green tea are catechins, of which epigallocatechin-3-gallate (EGCG) is the most abundant …

Modulation of signaling pathways in prostate cancer by green tea polyphenols

N Khan, H Mukhtar - Biochemical pharmacology, 2013 - Elsevier
Prostate cancer (PCa) is the most common malignancy found in American men and the risk
factors for PCa include age, family history, ethnicity, hormonal status, diet and lifestyle. For …

Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer

EC Stuart, MJ Scandlyn, RJ Rosengren - Life sciences, 2006 - Elsevier
Green tea and its major constituent epigallocatechin gallate (EGCG) have been extensively
studied as a potential treatment for a variety of diseases, including cancer. Epidemiological …

Epigallocatechin-3-gallate therapeutic potential in cancer: mechanism of action and clinical implications

M Kciuk, M Alam, N Ali, S Rashid, P Głowacka… - Molecules, 2023 - mdpi.com
Cellular signaling pathways involved in the maintenance of the equilibrium between cell
proliferation and apoptosis have emerged as rational targets that can be exploited in the …