[HTML][HTML] Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

DR Wang, XL Wu, YL Sun - Signal transduction and targeted therapy, 2022 - nature.com
Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …

[PDF][PDF] Top 10 challenges in cancer immunotherapy

PS Hegde, DS Chen - Immunity, 2020 - cell.com
Cancer immunotherapy is a validated and critically important approach for treating patients
with cancer. Given the vast research and clinical investigation efforts dedicated to advancing …

Cancer immunotherapy

CN Baxevanis, SA Perez… - Critical reviews in clinical …, 2009 - Taylor & Francis
Recent scientific advances have expanded our understanding of the immune system and its
response to malignant cells. The clinical goal of tumour immunotherapy is to provide either …

[HTML][HTML] Novel technologies and emerging biomarkers for personalized cancer immunotherapy

J Yuan, PS Hegde, R Clynes, PG Foukas… - … for immunotherapy of …, 2016 - Springer
The culmination of over a century's work to understand the role of the immune system in
tumor control has led to the recent advances in cancer immunotherapies that have resulted …

[HTML][HTML] Advances in cancer immunotherapy in solid tumors

S Menon, S Shin, G Dy - Cancers, 2016 - mdpi.com
Immunotherapy is heralded as one of the most important advances in oncology. Until
recently, only limited immunotherapeutic options were available in selected immunogenic …

Emerging opportunities and challenges in cancer immunotherapy

TL Whiteside, S Demaria, ME Rodriguez-Ruiz… - Clinical Cancer …, 2016 - AACR
Immunotherapy strategies against cancer are emerging as powerful weapons for treatment
of this disease. The success of checkpoint inhibitors against metastatic melanoma and …

[HTML][HTML] A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet

G D'Errico, HL Machado, B Sainz - Clinical and translational medicine, 2017 - Springer
Immunotherapy is the new trend in cancer treatment due to the selectivity, long lasting
effects, and demonstrated improved overall survival and tolerance, when compared to …

[HTML][HTML] Cancer immunotherapy, part 3: challenges and future trends

CL Ventola - Pharmacy and Therapeutics, 2017 - ncbi.nlm.nih.gov
During the past few decades, research has provided breakthroughs that have enhanced our
understanding of the mechanisms and pathways that regulate the immune system's …

Immunotherapy of cancer

H Borghaei, MR Smith, KS Campbell - European journal of pharmacology, 2009 - Elsevier
Major advances have been made in the field of immunology in the past two decades. A
better understanding of the molecular and cellular mechanisms controlling the immune …

Immunologic biomarkers as correlates of clinical response to cancer immunotherapy

ML Disis - Cancer immunology, immunotherapy, 2011 - Springer
Over the last few years, several newly developed immune-based cancer therapies have
been shown to induce clinical responses in significant numbers of patients. As a result, there …