Chemical property estimation is a key component in many industrial, academic, and
regulatory activities, including in the risk assessment associated with the approximately …

Abstract Structure-Activity Relationships (SAR) have been used for over a decade by the US
EPA's Office of Pollution Prevention and Toxics (OPPT) in their new chemicals program. The …

The use of quantitative structure‐activity relationships (QSARs) for deriving the predicted no‐
effect concentration of discrete organic chemicals for the purposes of conducting a …

As the regulatory incentives to provide data on commercial chemicals increases, there will
be greater opportunities to apply Quantitative Structure Activity Relationships (QSARs) and …

Reliable chemical property data are the key to defensible and unbiased assessments of
chemical emissions, fate, hazard, exposure, and risks. However, the retrieval, evaluation …

Section 5 of the Toxic Substances Control Act (TSCA) does not require any toxicity testing as
a prerequisite for submission of a Premanufacturing Notice (PMN) for a new chemical. In …

Ecological risk assessments for chemical stressors are used to establish linkages between
likely exposure concentrations and adverse effects to ecological receptors. At times, it is …

Abstract Structure-activity relationship (SAR) and quantitative structure-activity relationship
(QSAR), collectively referred to as (Q) SARs, play an important role in ecological risk …

Section 5 of the Toxic Substances Control Act (TSCA) requires that manufacturers and
importers of new chemicals must submit a Premanufacture Notification (PMN) to the US …

New techniques and software have enabled ubiquitous use of structure‐activity
relationships (SARs) in the pharmaceutical industry and toxicological sciences. We review …