Eumelanin photoprotects pigmented tissues from ultraviolet (UV) damage. However, UVA‐
induced tanning seems to result from the photooxidation of preexisting melanin and does …

Eumelanin is photoprotective while pheomelanin is phototoxic to pigmented tissues.
Ultraviolet A (UVA)‐induced tanning seems to result from the photooxidation of pre‐existing …

Soluble melanin precursors are present in serum and may act as skin chromophores
contributing to UVR‐in‐duced oxidative damage. Our study aimed to determine whether the …

To inquire into the role of the carboxyl group as determinant of the properties of 5, 6‐
dihydroxyindole melanins, melanins from aerial oxidation of 5, 6‐dihydroxyindole‐2 …

Eumelanin is photoprotective for pigmented tissues while pheomelanin is phototoxic. In this
review, we summarize current understanding of how eumelanin and pheomelanin structures …

Exposure to excess ultraviolet (UV) A radiation induces the degradation/modification of both
eumelanin and pheomelanin that may be deleterious to pigmented tissues. Although the …

Ultraviolet radiation (UVR) is one of the risk factors for skin cancer and the main inducer of
melanin pigmentation, the major protective mechanism of mammalian skin against radiation …

Diffusible melanin-related metabolites have recently been suggested to subserve a variety
of functions that are critical for protection of skin against inflammatory stimuli and oxidative …

Studies to UV-irradiate natural eumelanins in vitro have used insoluble pigment obtained by
acid hydrolysis, which lacks melanoprotein. Eumelanin synthesised in the presence of a …

In this work, we examined photoreactivity of synthetic eumelanins, formed by autooxidation
of DOPA, or enzymatic oxidation of 5, 6‐dihydroxyindole‐2‐carboxylic acid and synthetic …