Prostate cancer is one of the most common malignancies in men worldwide. Current clinical
screening ensures that most prostate cancers are diagnosed while still organ confined, but …

Aberrant DNA methylation is one of the hallmarks of carcinogenesis and has been
recognized in cancer cells for more than 20 years. The role of DNA methylation in malignant …

The protective effects of fruits, vegetables, and other foods on prostate cancer may be due to
their antioxidant properties. An imbalance in the oxidative stress/antioxidant status is …

Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

Introduction 3. DNA Hypermethylation, Heterochromatin, and Epigenetic Gene Silencing 4.
DNA Hypomethylation, Demethylation, and Loss of Imprinting 5. DNA Methyltransferases …

Epigenetic alterations contribute significantly to the development and progression of
prostate cancer, the most prevalent malignant tumor in males of Western industrialized …

Background DNA methylation has been linked to genome regulation and dysregulation in
health and disease respectively, and methods for characterizing genomic DNA methylation …

We examined the DNA methylation pathway in an autochthonous murine prostate cancer
model, transgenic adenocarcinoma of mouse prostate (TRAMP). We observed that …

Background Folate and methyl‐group deficiency has been linked to prostate cancer
susceptibility, yet the mechanisms underlying these observations are incompletely …

Epigenetic modifications, such as DNA methylation, are widely studied in cancer as they are
stable and easy to measure genome wide. DNA methylation changes have been used to …