Cytogenetics of childhood Acute Myeloid Leukemia: United Kingdom Medical Research
Council treatment trials AML 10 and 12 -ORCA Cardiff University | Prifysgol Caerdydd ORCA …

Purpose Karyotype is an independent indicator of prognosis in acute myeloid leukemia
(AML) that is widely applied to risk-adapted therapy. Because AML is rare in children, the …

Abstract Abstract 4688 Background Acquired clonal chromosomal alterations are common
and considered to have prognostic implications in acute myeloid leukemia (AML). Although …

Specific cytogenetic aberrations in acute myeloblastic leukemia (AML) have been found to
have important, independent prognostic significance. Consistent incidence of variations of …

The whole spectrum of chromosomal abnormalities and their prognostic significance in
children and adolescents with acute myeloid leukemia (AML) has not been fully elucidated …

In childhood‐onset acute myeloid leukaemia (AML) the clinical value of karyotypic
aberrations is now acknowledged, although there is still debate concerning the prognostic …

Although acute myeloid leukaemia (AML) has long been recognized for its morphological
and cytogenetic heterogeneity, recent high‐resolution genomic profiling has demonstrated a …

Within the last two decades several nonrandom acquired karyotype abnormalities have
been identified in acute myoblasts leukemia (AML). These abnormalities are specifically …

Acute myeloid leukemia (AML) accounting for approximately 17% of all childhood acute
leukemias, arises either de novo or from a backround of myelodysplasia or previous …

Cytogenetics is important in diagnosis of acute myeloid leukaemia (AML) and a number of
chromosomal abnormalities have prognostic significance. AML clinical trials use three …