Pathophysiological association of alzheimer's disease and hypertension: A clinical concern for elderly population

Q Yao, K Jiang, F Lin, T Zhu, NH Khan… - Clinical Interventions in …, 2023 - Taylor & Francis
Abstract Alzheimer's disease (AD), the most common cause of dementia and the fifth leading
cause of death in the adult population has a complex pathophysiological link with …

[HTML][HTML] Effects of Hypertension on Alzheimer's Disease: Updates in Pathophysiological and Neuroimaging Findings

SC Yan, L Liu, GL Fang, ST Weng, JJ Wang… - Journal of Integrative …, 2024 - imrpress.com
Alzheimer's disease (AD) is recognized as the leading cause of dementia, imposing a
significant economic toll on society. Despite the emergence of novel therapeutic approaches …

[HTML][HTML] Hypertension and dementia: epidemiological and experimental evidence revealing a detrimental relationship

M Perrotta, G Lembo, D Carnevale - International journal of molecular …, 2016 - mdpi.com
Hypertension and dementia represent two major public health challenges worldwide,
notably in the elderly population. Although these two conditions have classically been …

Anti-Hypertensive Drugs Moderate the Relationship of Blood Pressure with Alzheimer's Pathologies and Neurodegenerative Markers in Non-Demented Hypertensive …

Y Guo, CC Tan, MS Tan, L Tan, W Xu… - The Journal of …, 2024 - Springer
Background We aimed to explore whether the relationships of blood pressures (BPs) with
Alzheimer's disease (AD) endophenotypes varied by usage of antihypertensive drugs …

Update on hypertension and Alzheimer's disease

I Skoog, D Gustafson - Neurological research, 2006 - Taylor & Francis
Several studies report that blood pressure is increased in victims of Alzheimer's disease
(AD) decades before the onset of the disease. Years before onset of Alzheimer's disease …

[HTML][HTML] Hypertension and cognitive impairment: a review of mechanisms and key concepts

M Canavan, MJ O'Donnell - Frontiers in Neurology, 2022 - frontiersin.org
Cognitive impairment, and dementia, are major contributors to global burden of death and
disability, with projected increases in prevalence in all regions of the world, but most marked …

[HTML][HTML] Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer's disease

E Bajwa, A Klegeris - Neural Regeneration Research, 2022 - journals.lww.com
Alzheimer's disease, the most common type of dementia among older adults, currently
cannot be prevented or effectively treated. Only a very small percentage of Alzheimer's …

Hypertension and inflammation in Alzheimer's disease: close partners in disease development and progression!

L Nelson, P Gard, N Tabet - Journal of Alzheimer's Disease, 2014 - content.iospress.com
Alzheimer's disease (AD) is by far the most common sporadic neurodegenerative disorder.
Clinically it is associated with cognitive and other neuropsychological impairments, and …

Hypertension and Alzheimer Disease: Another Brick in the Wall of Awareness

E Thorin - Hypertension, 2015 - Am Heart Assoc
soluble Aβ42. It is not unusual to observe such endothelial overcompensation in response to
metabolic stress induced by transient brain ischemia, for example, but these adaptive …

Hypertension-related risk for dementia: A summary review with future directions

AM Daugherty - Seminars in Cell & Developmental Biology, 2021 - Elsevier
Chronic hypertension, or high blood pressure, is the most prevalent vascular risk factor that
accelerates cognitive aging and increases risk for Alzheimer's disease and related …