Organization of cancer cells into endothelial-like cell-lined structures to support
neovascularization and to fuel solid tumors is a hallmark of progression and poor outcome …

Triple negative breast cancer (TNBC) is a very aggressive subgroup of breast carcinoma,
still lacking specific markers for an effective targeted therapy and with a poorer prognosis …

Triple‑negative breast cancer (TNBC) is characterized by strong invasiveness, frequent local
recurrence and distant metastasis, with poor prognosis. According to tumor angiogenesis …

Metastastic breast cancer, especially triple-negative (TN), is one of the most common causes
of cancer related deaths in women. Recent years, tumor-associate vessel formation is …

MicroRNAs (miRNAs) are small endogenously produced RNAs, which regulate growth and
development, and oncogenic miRNA regulate tumor growth and metastasis. Tumour …

Recent studies suggested that cancer stem cells (CSCs) are capable of differentiating into
endothelial cells and tumor endothelium may be derived from CSCs. But the mechanism …

Claudin-low tumors are a highly aggressive breast cancer subtype with no targeted
treatments and a clinically documented resistance to chemotherapy. They are significantly …

The identification of prognostic biomarkers and their underlying mechanisms of action
remain of great interest in breast cancer biology. Using global miRNA profiling of 71 lymph …

Abstract Based on Stephen Paget's well-established theory, both cell-autonomous and non-
cell-autonomous mechanisms are crucial for metastasis. Although the mitochondrial calcium …

Background/Aims: Triple-negative breast cancer (TNBC) is the most aggressive breast
cancer subtype. Our study investigated the functional role of miR-212-5p in TNBC. Methods …