Lysine acetylation is an important posttranslational modification (PTM) that regulates the
function of proteins by affecting their localization, stability, binding, and enzymatic activity …

Due to the key role of posttranslational modifications (PTMs) such as lysine acetylation in
numerous signaling and regulatory pathways, the ability to identify novel PTMs and to …

The acetylation of proteins at specific lysine residues by acetyltransferase enzymes has
emerged as a posttranslational modification of high biological impact. Although lysine …

Lysine acetylation is a common protein posttranslational modification that regulates a variety
of biological processes. A major bottleneck to fully understanding the functional aspects of …

Posttranslational modifications of proteins control many complex biological processes,
including genome expression, chromatin dynamics, metabolism, and cell division through a …

Lysine acetylation is a widespread posttranslational modification (PTM) in all kingdoms of
live. A large number of proteins involved in most of biological pathways are targets of this …

The dynamic nature of protein posttranslational modification (PTM) allows cells to rapidly
respond to changes in their environment, such as nutrition, stress, or signaling. Lysine …

Histone acetylation is involved in gene regulation and, most importantly, aberrant regulation
of histone acetylation is correlated with major human diseases. Although many lysine …

With the emergence of the histone code as a key determinant in the regulation of gene
expression, it has been important to develop tools that can not only identify the types and …

Histone acetyltransferases (HATs, also known as lysine acetyltransferases, KATs) catalyze
acetylation of their cognate protein substrates using acetyl‐CoA (Ac‐CoA) as a cofactor and …