Acetylation of proteins on specific lysine residues by acetyltransferase enzymes is a post-
translational modification for biologically relevant regulation. In this study, we proposed a …

Introduction of antibodies specific for acetylated lysine has significantly improved the
detection of endogenous acetylation sites by mass spectrometry. Here, we describe a new …

As a key post-translational modification mechanism, protein acetylation plays critical roles in
regulating and/or coordinating cell metabolism. Acetylation is a prevalent modification …

Protein posttranslational modification (PTM) is a biochemical mechanism benefitting cellular
adaptation to dynamic intracellular and environmental conditions. Recently, several …

Acetylation is a common PTM of proteins but is still challenging to analyze. Only few
acetylome studies have been performed to tackle this issue. Yet, the detection of acetylated …

Histone acetylation has long been determined as a highly dynamic modification associated
with open chromatin and transcriptional activation. Here we develop a metabolic labelling …

The acetylation isoforms of histone H4 from butyrate-treated HeLa cells were separated by C
4 reverse-phase high pressure liquid chromatography and by polyacrylamide gel …

Acetylation is a highly abundant and dynamic post-translational modification (PTM) on
histone proteins which, when present on chromatin-bound histones, facilitates the …

A robust signaling network is essential for cell survival. At the molecular level, this is often
mediated by as many as 200 different types of post‐translational modifications (PTMs) that …

Regulation of histone acetylation is fundamental to the utilization of eukaryotic genomes in
chromatin. Aberrant acetylation contributes to disease and can be clinically combated by …