Clinical tolerability of artesunate-amodiaquine versus comparator treatments for uncomplicated falciparum malaria: an individual-patient analysis of eight randomized …

J Zwang, G Dorsey, A Djimdé, C Karema… - Malaria journal, 2012 - Springer
Background The widespread use of artesunate-amodiaquine (ASAQ) for treating
uncomplicated malaria makes it important to gather and analyse information on its …

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

… Antimalarial Resistance Network (WWARN) AS-AQ … - BMC medicine, 2015 - Springer
Abstract Background Artesunate-amodiaquine (AS-AQ) is one of the most widely used
artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium …

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

J Zwang, P Olliaro, H Barennes, M Bonnet, P Brasseur… - Malaria journal, 2009 - Springer
Background Artesunate and amodiaquine (AS&AQ) is at present the world's second most
widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the …

Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum …

B Schramm, P Valeh, E Baudin, CS Mazinda, R Smith… - Malaria Journal, 2013 - Springer
Background Safety surveillance of widely used artemisinin-based combination therapy
(ACT) is essential, but tolerability data in the over five years age group are largely anecdotal …

Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal

P Brasseur, P Agnamey, O Gaye… - Tropical Medicine & …, 2009 - Wiley Online Library
Objectives Several products of artesunate plus amodiaquine (AS+ AQ) are being deployed
in malaria‐endemic countries for treating uncomplicated falciparum malaria but dosing …

Safety and tolerability of artesunate-amodiaquine, artemether-lumefantrine and quinine plus clindamycin in the treatment of uncomplicated Plasmodium falciparum …

Y Lula Ntamba, H Muhindo Mavoko, M Kalabuanga… - PLoS …, 2019 - journals.plos.org
Introduction Artemisinin-based combination therapy is currently the best option for the
treatment of uncomplicated malaria. Quinine is recommended as a rescue treatment. Safety …

Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination …

J Zwang, JL Ndiaye, A Djimdé, G Dorsey… - Malaria journal, 2012 - Springer
Abstract Background Artesunate-amodiaquine (AS&AQ) is a widely used artemisinin
combination therapy (ACT) for falciparum malaria. A comprehensive appreciation of its …

Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the …

JLA Ndiaye, B Faye, AM Diouf, T Kuété, M Cisse… - Malaria Journal, 2008 - Springer
Background Artesunate plus amodiaquine is a coblistered ACT, given as a single daily
intake. It has been suggested that, in view of the number of tablets to be taken (particularly in …

High cure rates and tolerability of artesunate–amodiaquine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Kibaha and …

CI Mandara, F Francis, MG Chiduo, B Ngasala… - Malaria journal, 2019 - Springer
Abstract Background The Tanzanian National Malaria Control Programme (NMCP) and its
partners have been implementing regular therapeutic efficacy studies (TES) to monitor the …

Open-label, randomized, non-inferiority clinical trial of artesunate-amodiaquine versus artemether-lumefantrine fixed-dose combinations in children and adults with …

OA Toure, SB Assi, TL N'Guessan, GE Adji, AB Ako… - Malaria Journal, 2014 - Springer
Background Emergence of artemisinin resistance has raised concerns that the most potent
anti-malarial drug may be under threat. Artesunate-amodiaquine (AS-AQ) and artemether …