Biomarkers and biomeasures: key enablers for pharmacokinetic–pharmacodynamic modeling in drug discovery and development

BM Agoram, PH van der Graaf - Bioanalysis, 2012 - Taylor & Francis
For reprint orders, please contact reprints@ future-science. com and can be turned around
quickly has been critical to this development. The increased complexity of systems …

[引用][C] Trends in clinical pharmacology and therapeutics

IK Minichmayr, DM Smith, KM Giacomini… - Clinical …, 2023 - Wiley Online Library
Since its launch in 1960, Clinical Pharmacology & Therapeutics (CPT) has evolved as a
crossdisciplinary premier journal in clinical pharmacology. The editorial leadership of CPT …

Data digitizing: accurate and precise data extraction for quantitative systems pharmacology and physiologically‐based pharmacokinetic modeling

JG Wojtyniak, H Britz, D Selzer… - CPT …, 2020 - Wiley Online Library
In quantitative systems pharmacology (QSP) and physiologically‐based pharmacokinetic
(PBPK) modeling, data digitizing is a valuable tool to extract numerical information from …

GPS for QSP: a summary of the ACoP6 symposium on quantitative systems pharmacology and a stage for near‐term efforts in the field

CJ Musante, DR Abernethy… - CPT …, 2016 - Wiley Online Library
Quantitative Systems Pharmacology (QSP) is experiencing increased application in the drug
discovery and development process. Like its older sibling, systems biology, the QSP field is …

Beyond deterministic models in drug discovery and development

I Irurzun-Arana, C Rackauckas, TO McDonald… - Trends in …, 2020 - cell.com
The model-informed drug discovery and development paradigm is now well established
among the pharmaceutical industry and regulatory agencies. This success has been mainly …

[图书][B] Encyclopedia of biopharmaceutical statistics-four volume set

SC Chow - 2018 - taylorfrancis.com
Since the publication of the first edition in 2000, there has been an explosive growth of
literature in biopharmaceutical research and development of new medicines. This …

[图书][B] Drug design strategies: Quantitative approaches

DJ Livingstone, AM Davis - 2012 - books.google.com
This book brings together drug design practitioners, all leaders in their field, who are actively
advancing the field of quantitative methods to guide drug discovery, from structure-based …

Quantitative disease, drug, and trial models

JVS Gobburu, LJ Lesko - Annual review of pharmacology and …, 2009 - annualreviews.org
Quantitative disease-drug-trial models allow learning from prior experience and summarize
the knowledge in a ready to apply format. Employing these models to plan future …

Pharmacometrics: A New Era of Pharmacotherapy and Drug Development in Low‐and Middle‐Income Countries

M Usman, S Khadka, M Saleem… - Advances in …, 2023 - Wiley Online Library
Pharmacotherapy, in many cases, is practiced at a suboptimal level of performance in low‐
and middle‐income countries (LMICs) although stupendous amounts of data are available …

[图书][B] Essential statistics for the pharmaceutical sciences

P Rowe - 2015 - books.google.com
Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in
research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody …