Biomarkers and biomeasures: key enablers for pharmacokinetic–pharmacodynamic modeling in drug discovery and development
BM Agoram, PH van der Graaf - Bioanalysis, 2012 - Taylor & Francis
For reprint orders, please contact reprints@ future-science. com and can be turned around
quickly has been critical to this development. The increased complexity of systems …
quickly has been critical to this development. The increased complexity of systems …
[引用][C] Trends in clinical pharmacology and therapeutics
IK Minichmayr, DM Smith, KM Giacomini… - Clinical …, 2023 - Wiley Online Library
Since its launch in 1960, Clinical Pharmacology & Therapeutics (CPT) has evolved as a
crossdisciplinary premier journal in clinical pharmacology. The editorial leadership of CPT …
crossdisciplinary premier journal in clinical pharmacology. The editorial leadership of CPT …
Data digitizing: accurate and precise data extraction for quantitative systems pharmacology and physiologically‐based pharmacokinetic modeling
JG Wojtyniak, H Britz, D Selzer… - CPT …, 2020 - Wiley Online Library
In quantitative systems pharmacology (QSP) and physiologically‐based pharmacokinetic
(PBPK) modeling, data digitizing is a valuable tool to extract numerical information from …
(PBPK) modeling, data digitizing is a valuable tool to extract numerical information from …
GPS for QSP: a summary of the ACoP6 symposium on quantitative systems pharmacology and a stage for near‐term efforts in the field
CJ Musante, DR Abernethy… - CPT …, 2016 - Wiley Online Library
Quantitative Systems Pharmacology (QSP) is experiencing increased application in the drug
discovery and development process. Like its older sibling, systems biology, the QSP field is …
discovery and development process. Like its older sibling, systems biology, the QSP field is …
Beyond deterministic models in drug discovery and development
I Irurzun-Arana, C Rackauckas, TO McDonald… - Trends in …, 2020 - cell.com
The model-informed drug discovery and development paradigm is now well established
among the pharmaceutical industry and regulatory agencies. This success has been mainly …
among the pharmaceutical industry and regulatory agencies. This success has been mainly …
[图书][B] Encyclopedia of biopharmaceutical statistics-four volume set
SC Chow - 2018 - taylorfrancis.com
Since the publication of the first edition in 2000, there has been an explosive growth of
literature in biopharmaceutical research and development of new medicines. This …
literature in biopharmaceutical research and development of new medicines. This …
[图书][B] Drug design strategies: Quantitative approaches
DJ Livingstone, AM Davis - 2012 - books.google.com
This book brings together drug design practitioners, all leaders in their field, who are actively
advancing the field of quantitative methods to guide drug discovery, from structure-based …
advancing the field of quantitative methods to guide drug discovery, from structure-based …
Quantitative disease, drug, and trial models
JVS Gobburu, LJ Lesko - Annual review of pharmacology and …, 2009 - annualreviews.org
Quantitative disease-drug-trial models allow learning from prior experience and summarize
the knowledge in a ready to apply format. Employing these models to plan future …
the knowledge in a ready to apply format. Employing these models to plan future …
Pharmacometrics: A New Era of Pharmacotherapy and Drug Development in Low‐and Middle‐Income Countries
Pharmacotherapy, in many cases, is practiced at a suboptimal level of performance in low‐
and middle‐income countries (LMICs) although stupendous amounts of data are available …
and middle‐income countries (LMICs) although stupendous amounts of data are available …
[图书][B] Essential statistics for the pharmaceutical sciences
P Rowe - 2015 - books.google.com
Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in
research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody …
research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody …