Objective: Achievement of blood pressure (BP) targets in hypertension is crucial for
cardiovascular prevention and, in most cases, requires combined pharmacological …

The goal of antihypertensive therapy is to abolish the risks associated with blood pressure
(BP) elevation without adversely affecting quality of life. Control of hypertension and …

In the late 1960s and early 1970s, Freis et al. demonstrated convincingly that the
administration of antihypertensive drugs was associated with a marked reduction in target …

Arterial hypertension is a widely prevalent risk factor for cardiovascular diseases with well
documented harmful effects on the heart and the vascular system. Despite a broad …

Fixed dose formulations of rational antihypertensive drug combinations are being used
increasingly early in the management of hypertension (1). Fixed combinations for …

The majority of patients with hypertension need at least two antihypertensive agents to
achieve blood pressure (BP) objectives. As current European guidelines for the treatment of …

Hypertension is one of the most important risk factors for death, heart failure, ischaemic heart
disease, stroke and chronic kidney disease. Treatment of hypertension, particularly to goal …

A panel was convened to discuss current combination therapy for hypertension. Alan H.
Gradman, MD, of the Western Pennsylvania Hospital, Temple University School of Medicine …

The latest guidelines for the treatment of hypertension recommend stratification of blood
pressure (BP) goals according to patient risk level. For example, the recommended BP goal …

We provide a review of recent additions to the antihypertensive armamentarium in the form
of combination therapy. These include two-drug and three-drug combinations in a single pill …