Back in 1931, it was thought that “the treatment of hypertension itself is a difficult and almost
hopeless task… for ought we know the hypertension may be an important compensatory …

Raised levels of blood pressure result from the complex interplay of environmental and
genetic factors. The complexity of blood pressure control mechanisms has major …

Pharmacological treatment of hypertension represents a cost-effective way of preventing
cardiovascular and renal complications. To benefit maximally from antihypertensive …

Antihypertensive monotherapy, although commonly used, does not address the
multifactorial nature of hypertension as a disease with many pathways. Using more than one …

Hypertension is a serious global issue and major preventable risk factor for various
cardiovascular (CV) diseases such as coronary heart disease (CAD), stroke, heart failure …

The goal of antihypertensive therapy is to reduce the risk associated with blood pressure
elevation. Although the choice of first-line drug therapy may exert some effects on different …

Recent clinical trials in hypertension prove how seldom single drug therapy achieves target
blood pressure (BP) and reduces cardiovascular morbidity and mortality. A natural response …

CONCLUSIONS The 5 main categories of blood pressure (BP)-lowering drugs give similar
reductions in BP. Within each drug category, individual drugs give similar BP reductions …

Almost one billion individuals worldwide are currently estimated to be affected by
hypertension, or high blood pressure, with this figure predicted to rise to over 1.5 billion by …