Secukinumab loss of efficacy is perfectly counteracted by the introduction of combination therapy (rescue therapy): data from a multicenter real-life study in a cohort of …

G Damiani, G Odorici, A Pacifico, A Morrone… - Pharmaceuticals, 2022 - mdpi.com
Since psoriasis (PsO) is a chronic inflammatory disease, patients may experience a drug
failure also with very effective drugs (ie, secukinumab) and, consequently, dermatologists …

Long‐term continuation with secukinumab in psoriasis: association with patient profile and initial psoriasis clearance

L Ferrières, MP Konstantinou… - Clinical and …, 2019 - academic.oup.com
Background There are limited data regarding the long‐term continuation with biological
therapy for patients with psoriasis. In particular, the reasons for secukinumab discontinuation …

Treatment of patients with plaque psoriasis with secukinumab in a real-life setting: a 52-week, multicenter, retrospective study in Spain

J Notario, G Deza, E Vilarrasa, F Valentí… - Journal of …, 2019 - Taylor & Francis
Background: The efficacy and safety of secukinumab in patients with plaque psoriasis (PsO)
have been demonstrated in randomized clinical trials (RCTs). However, data regarding its …

Secukinumab drug survival in patients with psoriasis: a multicenter, real-world, retrospective study

T Torres, A Balato, C Conrad, A Conti, P Dapavo… - Journal of the American …, 2019 - jaad.org
To evaluate drug survival of secukinumab in a daily practice setting, we retrospectively
evaluated all psoriatic patients starting secukinumab during January 2016-February 2017 at …

Multicenter retrospective study of secukinumab drug survival in psoriasis patients in a daily practice setting: a long-term experience in Spain

E Daudén, GPG de Lima, S Armesto… - Dermatology and …, 2021 - Springer
Introduction There is limited and conflicting evidence over the real-world drug survival of
secukinumab (SEC) in patients with psoriasis, especially in the long term. Our objective was …

Long-term efficacy and safety of secukinumab in real life: a 240 weeks multicenter study from Southern Italy

S Dastoli, M Passante, F Loconsole… - Journal of …, 2023 - Taylor & Francis
Background Long-term real-life data on secukinumab use in psoriasis are limited. Objectives
Determine the long-term effectiveness of secukinumab in moderate-to-severe psoriasis in …

Effectiveness and safety of secukinumab in Italian patients with psoriasis: an 84 week, multicenter, retrospective real-world study

M Megna, L Di Costanzo, G Argenziano… - Expert Opinion on …, 2019 - Taylor & Francis
Background: Long term data on the real-life use of secukinumab are scant. The aim of this
study was to investigate the real-life effectiveness, safety and treatment persistence of …

Drug survival, discontinuation rates, and safety profile of secukinumab in real‐world patients: a 152‐week, multicenter, retrospective study

R Ruiz‐Villaverde… - International Journal …, 2020 - Wiley Online Library
Background Psoriasis is a chronic systemic disease that requires long‐term management.
Despite data on follow‐up studies going back 5 years, little is known about the condition's …

Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two phase III studies

M Lebwohl, L Iversen, L Eidsmo… - Clinical and …, 2023 - academic.oup.com
Background Secukinumab is effective against a range of psoriatic manifestations.
Investigating psoriasis (PsO) relapse following secukinumab discontinuation could provide …

Secukinumab sustains good efficacy and favourable safety in moderate‐to‐severe psoriasis after up to 3 years of treatment: results from a double‐blind extension …

R Bissonnette, T Luger, D Thaçi, D Toth… - British Journal of …, 2017 - academic.oup.com
Background Secukinumab has demonstrated significant efficacy with a good safety profile
through 1 year in plaque psoriasis. Given the chronic nature of this disease, long‐term follow …