Post-traumatic stress disorder (PTSD) is more prevalent in women than men, yet much
remains to be determined regarding the mechanism underlying this sex difference. Clinical …

Classical fear acquisition and extinction are important models for the etiology and treatment
of anxiety disorders such as posttraumatic stress disorder (PTSD). Women are at a higher …

Fear acquisition and extinction are valid models for the etiology and treatment of anxiety,
trauma-and stressor-related disorders. These disorders are assumed to involve aversive …

Posttraumatic stress disorder (PTSD) is a psychiatric illness whose prevalence in women is
more than twice the rate as men. Despite a burgeoning literature characterizing sex …

Fear extinction, the laboratory basis of exposure therapy for anxiety disorders, fluctuates
across the female rat estrous cycle, where extinction is enhanced during proestrus (high …

BACKGROUND: Men and women differ in their ability to extinguish fear. Fear extinction
requires the activation of brain regions, including the ventromedial prefrontal cortex (vmPFC) …

Fear extinction is the laboratory basis of exposure therapy for anxiety disorders. Recent
findings have revealed that estradiol is necessary to the consolidation of extinction …

Gonadal hormones modulate fear acquisition, but less is known about the influence of
gonadal hormones on fear extinction. We assessed sex differences and the influence of …

BACKGROUND: Women are twice as likely to develop posttraumatic stress disorder (PTSD)
than men. As shown in our previous work, the inability to suppress fear responses in safe …

Rationale Traumatic stress leads to persistent fear, which is a core feature of post-traumatic
stress disorder (PTSD). Women are more likely than men to develop PTSD after trauma …