The major mechanisms used by microorganisms to transport iron within the cell are through
chelation, reduction and low-affinity transport. Microbially-produced iron chelators are …

Although a stimulating review by JB Neilands in 1957 [1] correctly identified the
physiological function of certain microbial ferric chelators, it was in 1973 that Charles …

In Gram-negative bacteria an iron-deficient state is required for both induction of desferri-
siderophores and overproduction of the cognate outer membrane receptor proteins. Thus …

Microbial iron chelates, called siderophores, are synthesized by bacteria and fungi in
response to low iron availability in the environment. The present review summarizes …

Siderophores (from the Greek:“iron carriers”) are defined as relatively low molecular weight,
ferric ion specific chelating agents elaborated by bacteria and fungi growing under low iron …

▪ Abstract Iron is an essential element for most organisms, including bacteria. The oxidized
form is insoluble, and the reduced form is highly toxic for most macromolecules and, in …

Conspectus This Account focuses on the coordination chemistry of the microbial iron
chelators called siderophores. The initial research (early 1970s) focused on simple analogs …

The insolubility of Fe 3+ necessitates special mechanisms for iron acquisition in most
organisms. Bacteria use siderophores to chelate Fe 3+ and iron in heme, hemoglobin …

Microbial iron bioavailability is largely determined by the coordination chemistry associated
with the siderophores, a class of organic compounds which have a high and specific …

The present handbook seeks to bring into one book theoretical and practical information on
the various aspects of microbial iron chelates which are now collectively called …