[HTML][HTML] The nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human BST-2/Tetherin
S Giese, SP Lawrence, M Mazzon, BM Nijmeijer… - Viruses, 2020 - mdpi.com
Bone Marrow Stromal Cell Antigen 2 (BST-2)/tetherin inhibits the release of numerous
enveloped viruses by physically tethering nascent particles to infected cells during the …
enveloped viruses by physically tethering nascent particles to infected cells during the …
Efficient Vpu-mediated tetherin antagonism by an HIV-1 group O strain
K Mack, K Starz, D Sauter, S Langer… - Journal of …, 2017 - Am Soc Microbiol
Simian immunodeficiency viruses (SIVs) use their Nef proteins to counteract the restriction
factor tetherin. However, a deletion in human tetherin prevents antagonism by the Nef …
factor tetherin. However, a deletion in human tetherin prevents antagonism by the Nef …
Tetherin antagonism by HIV-1 group M Nef proteins
JF Arias, M Colomer-Lluch, B von Bredow… - Journal of …, 2016 - Am Soc Microbiol
Although Nef is the viral gene product used by most simian immunodeficiency viruses to
overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group …
overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group …
[PDF][PDF] Nef proteins from simian immunodeficiency viruses are tetherin antagonists
F Zhang, SJ Wilson, WC Landford, B Virgen… - Cell host & …, 2009 - cell.com
Summary The tetherin/BST2/CD317 protein blocks the release of HIV-1 and other
enveloped viruses by inducing tethering of nascent particles to infected cell surfaces. The …
enveloped viruses by inducing tethering of nascent particles to infected cell surfaces. The …
Preadaptation of simian immunodeficiency virus SIVsmm facilitated Env-mediated counteraction of human tetherin by human immunodeficiency virus type 2
E Heusinger, K Deppe, P Sette, C Krapp… - Journal of …, 2018 - Am Soc Microbiol
The host restriction factor tetherin inhibits virion release from infected cells and poses a
significant barrier to successful zoonotic transmission of primate lentiviruses to humans …
significant barrier to successful zoonotic transmission of primate lentiviruses to humans …
[HTML][HTML] Lack of adaptation to human tetherin in HIV-1 group O and P
SJ Yang, LA Lopez, CM Exline, KG Haworth… - Retrovirology, 2011 - Springer
Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite
the same genomic organization, only the group M viruses are responsible for the world-wide …
the same genomic organization, only the group M viruses are responsible for the world-wide …
[PDF][PDF] Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host
N Götz, D Sauter, SM Usmani, JV Fritz, C Goffinet… - Cell host & …, 2012 - cell.com
The interferon-induced host restriction factor tetherin poses a barrier for SIV transmission
from primates to humans. After cross-species transmission, the chimpanzee precursor of …
from primates to humans. After cross-species transmission, the chimpanzee precursor of …
[PDF][PDF] Nef proteins of epidemic HIV-1 group O strains antagonize human tetherin
Most simian immunodeficiency viruses use their Nef protein to antagonize the host
restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a …
restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a …
[PDF][PDF] Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV
Summary Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein that
inhibits virus release from infected cells. Whereas HIV-1 Vpu and HIV-2 Env counteract …
inhibits virus release from infected cells. Whereas HIV-1 Vpu and HIV-2 Env counteract …
[HTML][HTML] Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2
B Jia, R Serra-Moreno, W Neidermyer Jr… - PLoS …, 2009 - journals.plos.org
Tetherin, also known as BST2, CD317 or HM1. 24, was recently identified as an interferon-
inducible host–cell factor that interferes with the detachment of virus particles from infected …
inducible host–cell factor that interferes with the detachment of virus particles from infected …