Background HMG-CoA reductase inhibitors [statins], a widely prescribed cholesterol-
lowering therapy, are associated with muscle-related adverse events. While characteristics …

Objective To estimate the incidence of muscle toxicity in patients receiving statin therapy by
examining study populations, drug exposure status and outcome definitions. Design A …

Study Objective. To characterize the properties and natural history of 3–hydroxy‐3‐
methylglutaryl coenzyme A reductase inhibitor (statin)‐associated muscle‐related adverse …

Objective: To review the epidemiology, clinical features, proposed mechanisms, risk factors,
and management of statin-associated myopathy. Data Sources: Literature searches were …

Background: Statins are widely used in the treatment of hyperlipidemia and in the prevention
of cardiovascular diseases. However, they may induce muscular adverse effects that range …

Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are associated with
skeletal muscle complaints, including clinically important myositis and rhabdomyolysis, mild …

Background Statins are associated with skeletal muscle adverse effects. These are
generally considered mild and reversible, with more severe toxicity occurring rarely. There is …

AIM Statins are used in the treatment of hyperlipidaemia. They are among the most
commonly prescribed drugs worldwide. Statins have been linked to musculoskeletal …

Background: Statins are generally well tolerated, but muscular adverse effects appear to be
the most common obstacle limiting their use. Our objective was to describe the severity of …

INTRODUCTION—Statins are the primary class of medication used to lower serum
cholesterol concentration for both primary and secondary prevention of cardiovascular …