Our recent studies on tobacco smoke carcinogen and toxicant biomarkers and cancer risk
among male smokers in the Shanghai Cohort Study showed that exposure to tobacco …

It has been estimated that one in every five cancer deaths worldwide are related to tobacco
use. According to the IARC, 10 polycyclic aromatic hydrocarbons (PAH) and 8 tobacco …

Background Differences in carcinogen exposure from different cigarette products could
contribute to differences in smoking-associated cancer incidence among Chinese compared …

Metabolites of tobacco smoke constituents can be quantified in urine and other body fluids
providing a realistic measure of carcinogen and toxicant dose in a smoker. Many previous …

Introduction: The causal relationship between tobacco smoking and a variety of cancers is
attributable to the carcinogens that smokers inhale, including tobacco-specific nitrosamines …

The tobacco‐specific nitrosamines N′‐nitrosonornicotine (NNN) and 4‐
(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) are potent carcinogens for the rat …

We developed and applied high throughput liquid and gas chromatography–tandem mass
spectrometry (LC-MS/MS and GC-MS/MS) methods for the cigarette smoking-associated …

Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Nitrosamines are a class of carcinogens which have been detected widely in food, water,
some pharmaceuticals as well as tobacco. The objectives of this paper include reviewing the …

Smokeless tobacco has been proposed as a reduced risk substitute for smoking, but no
large studies have investigated exposure to the powerful carcinogen 4-(methylnitrosamino) …