Type 1 diabetes (T1D) is an autoimmune disease caused by the immune system attacking
and destroying insulin-producing β cells in the pancreas. Islet transplantation is becoming …

Clinical islet transplantation is an effective therapy in restoring physiological glycemic
control in type 1 diabetics. However, allogeneic islets derived from cadaveric sources elicit …

Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in the destruction of
insulin-secreting β cells of the islets of Langerhans. Allogeneic islet transplantation could be …

Islet transplantation is a promising curative treatment option for type 1 diabetes (T1D) as it
can provide physiological blood glucose control. The widespread utilization of islet …

Islet transplantation is an alternative method of replacing exogenous insulin to treat type 1
diabetes. However, transplantation of allo-or xenograft islets causes the activation of host's …

Abstract Type 1 diabetes (T1D) onset is characterized by an autoimmune attack on β islet
cells within the pancreas, preventing the insulin secretion required to maintain glucose …

Islet transplantation has shown promise as a curative therapy for type 1 diabetes (T1D).
However, the side effects of systemic immunosuppression and limited long‐term viability of …

As a newly emerging organ transplantation technique, islet transplantation has shown the
advantages of minimal trauma and high safety since it was first carried out. The proposal of …

The effective suppression of adaptive immune responses is essential for the success of
allogeneic cell therapies. In islet transplantation for Type 1 Diabetes, pre-existing …

Type 1 diabetes is an autoimmune disease in which the immune system attacks insulin-
producing beta cells of pancreatic islets. Type 1 diabetes can be treated with islet …