Control of antibody-antigen binding or dissociation by electric field

PB Oldham, AN Asanov - Systems and Technologies for …, 1999 - spiedigitallibrary.org
The development of a biosensor with adequate sensitivity generally requires a biospecific
interaction with high binding affinity. The affinity constants for most antibody-antigen …

The application of an applied electrical potential to generate electrical fields and forces to enhance affinity biosensors

DE Hagness, Y Yang, RD Tilley, JJ Gooding - Biosensors and …, 2023 - Elsevier
Affinity biosensors play a crucial role in clinical diagnosis, pharmaceuticals, immunology,
and other areas of human health. Affinity biosensors rely on the specific binding between …

Electrochemical modulation of antigen–antibody binding

JJ Gooding, C Wasiowych, D Barnett… - Biosensors and …, 2004 - Elsevier
The label-free amperometric detection of a rabbit IgG antigen by an anti-rabbit IgG antibody
is achieved by observing the electrochemistry at a glassy carbon electrode modified with …

Non-invasive control of protein-surface interactions for repeated electrochemical immunosensor use

MM Khoo, Z Rahim, NT Darwish, Y Alias… - Sensors and Actuators B …, 2016 - Elsevier
Although most immunosensors which have high affinity antigen–antibody interactions can
perform highly specific and sensitive detection, antibody–antigen bonds are typically too …

Electrical control over antibody–antigen binding

E Brod, S Nimri, B Turner, U Sivan - Sensors and Actuators B: Chemical, 2008 - Elsevier
We show that the binding of an antibody to its antigen can be controlled electrically in a
reversible manner. The antibody–antigen interaction is monitored by an electrochemical …

An amperometric biosensor for real-time analysis of molecular recognition

D Ivnitski, T Wolf, B Solomon, G Fleminger… - Bioelectrochemistry and …, 1998 - Elsevier
An amperometric, enzyme-channeling immunosensor was used to study the qualitative and
quantitative aspects of molecular biorecognition in real time. The immunosensor consisted …

An impedance array biosensor for detection of multiple antibody–antigen interactions

X Yu, R Lv, Z Ma, Z Liu, Y Hao, Q Li, D Xu - Analyst, 2006 - pubs.rsc.org
Electrochemical impedance spectroscopy (EIS) combined with a gold electrode array was
developed to detect multiple antibody–antigen interactions. Hepatitis B surface antigen …

[图书][B] Enhancement of Biomolecule Binding on Biosensors Using AC Electrokinetics

RW Hart, H Noh - 2010 - core.ac.uk
Biosensors generally rely on the reaction or attachment of an analyte with a solid support–
usually a bio-functionalized transducer. They can therefore suffer from transport limitations …

Electrochemical antibody-based sensors

J Rishpon, V Buchner - Comprehensive Analytical Chemistry, 2005 - Elsevier
Publisher Summary Antibody-based biosensors are based on the principle that antigen–
antibody interactions can be transduced directly into a measurable physical signal. This …

Antibody-and receptor-based biosensors for detection and process control

RF Taylor, IG Marenchic, RH Spencer - Analytica chimica acta, 1991 - Elsevier
The extension of a generic immobilization technology for the fabrication of antibody-and
receptor-based biosensors is reported. The biosensors utilize polymerized protein films …