[HTML][HTML] The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of …

K Kato, H Iwama, T Yamashita… - Oncology …, 2016 - spandidos-publications.com
Recent studies suggest that metformin, which is a commonly used oral anti-hyperglycemic
agent of the biguanide family, may reduce cancer risk and improve prognosis, yet the …

The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In Vivo

K Kato, J Gong, H Iwama, A Kitanaka, J Tani… - Molecular cancer …, 2012 - AACR
Recent studies suggest that metformin, which is commonly used as an oral anti-
hyperglycemic agent of the biguanide family, may reduce cancer risk and improve …

[HTML][HTML] Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo

H Miyoshi, K Kato, H Iwama… - International …, 2014 - spandidos-publications.com
Metformin is a commonly used oral anti-hyperglycemic agent of the biguanide family. Recent
studies suggest that metformin may reduce cancer risk and improve prognosis. However, the …

[HTML][HTML] Antitumor effect of metformin in esophageal cancer: in vitro study

M Kobayashi, K Kato, H Iwama… - International …, 2013 - spandidos-publications.com
Recent studies suggest that metformin, which is a member of the biguanide family and
commonly used as an oral anti-hyperglycemic agent, may reduce cancer risk and improve …

[HTML][HTML] How metformin affects various malignancies by means of microRNAs: a brief review

N Alimoradi, N Firouzabadi, R Fatehi - Cancer Cell International, 2021 - Springer
Metformin known as the first-line orally prescribed drug for lowering blood glucose in type II
diabetes (T2DM) has recently found various therapeutic applications including in cancer …

Crucial microRNAs and genes in metformin's anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis

Y Li, L Li, G Zhang, Y Wang, H Chen, R Kong… - Investigational New …, 2018 - Springer
Despite great improvements in surgical procedures and chemotherapy, pancreatic cancer
remains one of the most aggressive and fatal human malignancies, with a low 5-year …

[HTML][HTML] Antidiabetic drug metformin inhibits esophageal adenocarcinoma cell proliferation in vitro and in vivo

S Fujihara, K Kato, A Morishita… - International …, 2015 - spandidos-publications.com
Esophageal carcinoma is the eighth most common cancer worldwide and the sixth leading
cause of cancer-related deaths, with one of the worst prognoses of any form of cancer …

[HTML][HTML] Transcriptome analysis of liver cancer cell Huh-7 treated with metformin

CQ Li, ZQ Liu, SS Liu, GT Zhang, L Jiang… - Frontiers in …, 2022 - frontiersin.org
Metformin is a kind of widely used antidiabetic drug that regulates glucose homeostasis by
inhibiting liver glucose production and increasing muscle glucose uptake. Recently, some …

[HTML][HTML] Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies

T Fujimori, K Kato, S Fujihara, H Iwama… - Oncology …, 2015 - spandidos-publications.com
Cholangiocarcinoma (CCA) is the most common biliary malignancy and the second most
common hepatic malignancy after hepatocellular carcinoma (HCC). Treatment with the anti …

[HTML][HTML] Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and …

B Bao, AS Azmi, S Ali, F Zaiem… - Annals of translational …, 2014 - ncbi.nlm.nih.gov
Metformin is one of the most used diabetic drugs for the management of type II diabetes
mellitus (DM) in the world. Increased numbers of epidemiological and clinical studies have …