[HTML][HTML] Switching from an originator anti-TNF to a biosimilar in patients with inflammatory bowel disease: can it be recommended? A systematic review

JP Gisbert, M Chaparro - Gastroenterologia y Hepatologia, 2018 - Elsevier
Aim To review the effectiveness and safety of switching from an originator anti-TNF
(Remicade®) to a biosimilar (CT-P13) in patients with inflammatory bowel disease (IBD) …

Outcomes of patients with inflammatory bowel diseases switched from maintenance therapy with a biosimilar to Remicade

A Ilias, L Gonczi, Z Kurti, PA Golovics, K Farkas… - Clinical …, 2019 - Elsevier
Background & Aims There is evidence that it is safe and effective for patients with
inflammatory bowel diseases (IBD) to switch from maintenance therapy with an original …

Outcome of reverse switching from CT-P13 to originator infliximab in patients with inflammatory bowel disease

S Mahmmod, JPD Schultheiss… - Inflammatory Bowel …, 2021 - academic.oup.com
Background Patients suffering from inflammatory bowel diseases (IBD) and treated with
originator infliximab are increasingly being switched to biosimilars. Some patients, however …

Switching from infliximab to biosimilar in inflammatory bowel disease: overview of the literature and perspective

Á Milassin, A Fábián, T Molnár - Therapeutic advances in …, 2019 - journals.sagepub.com
Background: Biological therapy has revolutionized the treatment of inflammatory bowel
disease (IBD). After the expiration of patents for biological innovator products, development …

Switching from originator infliximab to the biosimilar CT-P13 in 313 patients with inflammatory bowel disease

V Bergqvist, M Kadivar, D Molin… - Therapeutic …, 2018 - journals.sagepub.com
Background: As the patents of originator biologics are expiring, biosimilar versions are
becoming available for the treatment of inflammatory bowel disease (IBD). However …

Evolution after switching to biosimilar infliximab in inflammatory bowel disease patients in clinical remission

LG Puente, EI Flores, JM Benítez, RM Medina… - … y Hepatología (English …, 2017 - Elsevier
Background and aim The biosimilar of infliximab (CT-P13) has been approved for the same
indications held by the infliximab reference product (Remicade®); however, there are few …

Switching from infliximab originator to a first biosimilar is safe and effective. Results of a case-control study with drug levels and antibodies evaluation

C Guiotto, A Italia, A Lavagna, C Rigazio… - Digestive and Liver …, 2019 - Elsevier
Background Inflammatory bowel disease is treated with anti-TNF agents such as infliximab
and its biosimilars, but use of biosimilars is limited due to perceived risks of adverse events …

Switching from originator infliximab to biosimilar versus continuing on originator in inflammatory bowel disease: results from the observational Project NORTH study

PM Hellström, E Gemmen, HA Ward… - Scandinavian Journal …, 2022 - Taylor & Francis
Objective Project NORTH compared real-world clinical and economic outcomes in Swedish
patients with inflammatory bowel disease (IBD) who switched from originator infliximab to its …

[PDF][PDF] Switching of patients with inflammatory bowel disease from original infliximab [Remicade®] to biosimilar infliximab [Remsima™] is effective and safe

M Kolar, D Duricova, M Brotlik, V Hruba… - J Crohns …, 2016 - academia.edu
Background: Biosimilar infliximab (IFX) seems to have similar efficacy and safety to original
preparation in patients with inflammatory bowel diseases (IBD) who are naïve to anti-TNFa …

Multiple switches from the originator infliximab to biosimilars is effective and safe in inflammatory bowel disease: a prospective multicenter cohort study

J Hanzel, JM Jansen, RWF Ter Steege… - Inflammatory bowel …, 2022 - academic.oup.com
Background Though a single nonmedical switch from the originator infliximab (IFX) to a
biosimilar is considered effective and safe for most patients with inflammatory bowel disease …