[HTML][HTML] Identification of PGRMC1 as a Candidate Oncogene for Head and Neck Cancers and Its Involvement in Metabolic Activities
Y Zhao, X Ruan - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
Progesterone Receptor Membrane Component 1 (PGRMC1/Sigma-2 receptor) is located on
chromosome Xq21 and encodes a haem-containing protein that interacts with epidermal …
chromosome Xq21 and encodes a haem-containing protein that interacts with epidermal …
Metabolism‐Related Bioinformatics Analysis Reveals That HPRT1 Facilitates the Progression of Oral Squamous Cell Carcinoma In Vitro
H Ye, Z Zheng, Y Song, G Huang, Q Wu… - Journal of …, 2022 - Wiley Online Library
Objectives. Many studies have shown that dysregulation of metabolism contributes to
oncogenesis. However, the exact roles of metabolism‐related genes (MRGs) in oral …
oncogenesis. However, the exact roles of metabolism‐related genes (MRGs) in oral …
Role of PGRMC1 in cell physiology of cervical cancer
CC Shih, HC Chou, YJ Chen, WH Kuo, CH Chan… - Life sciences, 2019 - Elsevier
Aims The most frequent cancers among women worldwide. The mortality of cervical cancer
has declined significantly primarily due to the widespread use of Pap smear tests as a …
has declined significantly primarily due to the widespread use of Pap smear tests as a …
Elevated progesterone receptor membrane component 1/sigma‐2 receptor levels in lung tumors and plasma from lung cancer patients
SUR Mir, ISA Ahmed, S Arnold… - International Journal of …, 2012 - Wiley Online Library
Cancer is one of the leading causes of death, and there is an urgent need for new
biomarkers and therapeutic targets. The progesterone receptor membrane component 1 …
biomarkers and therapeutic targets. The progesterone receptor membrane component 1 …
[HTML][HTML] Repression of GPRC5A is associated with activated STAT3, which contributes to tumor progression of head and neck squamous cell carcinoma
Background G protein–coupled receptor family C group 5 member A (GPRC5A), a retinoic
acid-inducible gene, is a lung tumor suppressor. Previously, we showed that repression of …
acid-inducible gene, is a lung tumor suppressor. Previously, we showed that repression of …
[HTML][HTML] PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity!
MA Cahill, JA Jazayeri, Z Kovacevic, DR Richardson - Oncotarget, 2016 - ncbi.nlm.nih.gov
Progesterone receptor membrane component 1 (PGRMC1) is a multifunctional protein
implicated in multiple pathologies, including cancer and Alzheimer's disease. The recently …
implicated in multiple pathologies, including cancer and Alzheimer's disease. The recently …
[HTML][HTML] PGRMC proteins are coming of age: a special issue on the role of PGRMC1 and PGRMC2 in metabolism and cancer biology
MA Cahill, H Neubauer - Cancers, 2021 - mdpi.com
This is a preface by the guest editors of the special issue of Cancers featuring the biology of
progesterone (P4) receptor membrane component (PGRMC) proteins as it relates to …
progesterone (P4) receptor membrane component (PGRMC) proteins as it relates to …
[HTML][HTML] Constructing a prognostic model for head and neck squamous cell carcinoma based on glucose metabolism related genes
Y Liu, N Liu, X Zhou, L Zhao, W Wei, J Hu… - Frontiers in …, 2023 - frontiersin.org
Background Glucose metabolism (GM) plays a crucial role in cancer cell proliferation, tumor
growth, and survival. However, the identification of glucose metabolism-related genes …
growth, and survival. However, the identification of glucose metabolism-related genes …
Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis
HY Huang, HC Chou, CH Law… - Journal of Cellular …, 2020 - Wiley Online Library
Cancer metastasis is a common cause of failure in cancer therapy. However, over 60% of
oral cancer patients present with advanced stage disease, and the five‐year survival rates of …
oral cancer patients present with advanced stage disease, and the five‐year survival rates of …
GPRC5A: an emerging biomarker in human cancer
X Jiang, X Xu, M Wu, Z Guan, X Su… - BioMed Research …, 2018 - Wiley Online Library
Aberrant expression of G protein‐coupled receptors (GPCRs) is frequently associated with
tumorigenesis. G Protein‐coupled receptor class C group 5 member A (GPRC5A) is a …
tumorigenesis. G Protein‐coupled receptor class C group 5 member A (GPRC5A) is a …