Background Fatigue has a major influence on the quality of life of people with multiple
sclerosis. The Fatigue Severity Scale is a frequently used patient-reported measure of …

Abstract Purpose The Fatigue Impact Scale (FIS) has been used extensively to assess the
impact of fatigue on health-related quality of life (HRQOL) in multiple sclerosis (MS). The …

Background Increasingly, generic preference-based measures of health-related quality of
life (HRQOL) are used to estimate quality-adjusted life-years to inform resource allocation …

Purpose To create cross-walk tables to associate scores for the Modified Fatigue Impact
Scale (MFIS) with scores for the Patient Reported Outcome Measurement Information …

Objective In economic evaluation, health outcomes are commonly quantified using quality-
adjusted life-years (QALYs) derived from the preferences of a sample of the general …

Background Fatigue is a common and debilitating symptom of Multiple Sclerosis (MS);
however, it is unknown what constitutes a clinically significant change in fatigue …

Introduction Physical fatigue can be a common reason for early retirement or sick leave
since it appears in the earliest stages of multiple sclerosis (MS). Therefore, a prompt and …

Background Condition-specific measures are frequently used to assess the health-related
quality of life of people with multiple sclerosis (MS). Such measures are unsuitable for use in …

Background: Increasing use of the Quality-Adjusted Life-Year to inform resource allocation
decision-making has highlighted the importance of relating clinical and health-related …

abstract Objectives To estimate health state utility values (HSUVs) for multiple sclerosis (MS)
by key demographic and clinical characteristics. Methods Data from a UK prospective …