Sulforaphane promotes mitochondrial protection in SH-SY5Y cells exposed to hydrogen peroxide by an Nrf2-dependent mechanism
MR de Oliveira, F de Bittencourt Brasil… - Molecular …, 2018 - Springer
Abstract Sulforaphane (SFN; C 6 H 11 NOS 2) is an isothiocyanate found in cruciferous
vegetables, such as broccoli, kale, and radish. SFN exhibits antioxidant, anti-apoptotic, anti …
vegetables, such as broccoli, kale, and radish. SFN exhibits antioxidant, anti-apoptotic, anti …
Naringenin Attenuates H2O2-Induced Mitochondrial Dysfunction by an Nrf2-Dependent Mechanism in SH-SY5Y Cells
MR de Oliveira, FB Brasil, CMB Andrade - Neurochemical Research, 2017 - Springer
Mitochondria are the major site of ATP production in mammalian cells. Furthermore, these
organelles are a source and a target of reactive oxygen species (ROS), such as radical …
organelles are a source and a target of reactive oxygen species (ROS), such as radical …
The isothiocyanate sulforaphane prevents mitochondrial impairment and neuroinflammation in the human dopaminergic SH-SY5Y and in the mouse microglial BV2 …
FB Brasil, FJS de Almeida, MD Luckachaki… - Metabolic Brain …, 2023 - Springer
Sulforaphane (SFN) promotes protective effects in different cell types. Nonetheless, it
remains to be clarified by which mechanism SFN exerts benefits in mammalian cells …
remains to be clarified by which mechanism SFN exerts benefits in mammalian cells …
Sulforaphane attenuated the pro-inflammatory state induced by hydrogen peroxide in SH-SY5Y cells through the Nrf2/HO-1 signaling pathway
MR de Oliveira, FB Brasil, CR Fürstenau - Neurotoxicity Research, 2018 - Springer
Sulforaphane (SFN), an isothiocyanate obtained from cruciferous vegetables, exerts
antioxidant, antiapoptotic, and antitumor activities in different cell types. Moreover, SFN has …
antioxidant, antiapoptotic, and antitumor activities in different cell types. Moreover, SFN has …
Effects of sulforaphane on brain mitochondria: mechanistic view and future directions
FR Jardim, FJS de Almeida, MD Luckachaki… - Journal of Zhejiang …, 2020 - Springer
The organosulfur compound sulforaphane (SFN; C 6 H 11 NOS 2) is a potent cytoprotective
agent promoting antioxidant, anti-inflammatory, antiglycative, and antimicrobial effects in in …
agent promoting antioxidant, anti-inflammatory, antiglycative, and antimicrobial effects in in …
Carnosic Acid Suppresses the H2O2-Induced Mitochondria-Related Bioenergetics Disturbances and Redox Impairment in SH-SY5Y Cells: Role for Nrf2
The phenolic diterpene carnosic acid (CA, C 20 H 28 O 4) exerts antioxidant, anti-
inflammatory, anti-apoptotic, and anti-cancer effects in mammalian cells. CA activates the …
inflammatory, anti-apoptotic, and anti-cancer effects in mammalian cells. CA activates the …
Tanshinone I Attenuates the Effects of a Challenge with H2O2 on the Functions of Tricarboxylic Acid Cycle and Respiratory Chain in SH-SY5Y Cells
MR de Oliveira, CR Fürstenau, ICC de Souza… - Molecular …, 2017 - Springer
Abstract Tanshinone I (TI; C 18 H 12 O 3) is a cytoprotective molecule. TI has been viewed
as an antioxidant and anti-inflammatory agent exerting neuroprotective actions in several …
as an antioxidant and anti-inflammatory agent exerting neuroprotective actions in several …
Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: a seemingly contradictory dual role and an integrative hypothesis
M Negrette-Guzmán, S Huerta-Yepez, E Tapia… - Free Radical Biology …, 2013 - Elsevier
The chemotherapeutic isothiocyanate sulforaphane (SFN) was early linked to
anticarcinogenic and antiproliferative activities. Soon after, this compound, derived from …
anticarcinogenic and antiproliferative activities. Soon after, this compound, derived from …
Succinobucol, a lipid-lowering drug, protects against 3-nitropropionic acid-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y cells via upregulation of …
D Colle, DB Santos, JM Hartwig, M Godoi… - Molecular …, 2016 - Springer
Succinobucol (succinyl ester of probucol) is a lipid-lowering compound with anti-
inflammatory and antioxidant properties. Recent experimental evidence has highlighted the …
inflammatory and antioxidant properties. Recent experimental evidence has highlighted the …
Tanshinone I induces mitochondrial protection through an Nrf2-dependent mechanism in paraquat-treatedhuman neuroblastoma SH-SY5Y cells
MR de Oliveira, PF Schuck, SMD Bosco - Molecular Neurobiology, 2017 - Springer
Abstract Tanshinone I (TI; 1, 6-Dimethylnaphtho [1, 2-g][1] benzofuran-10, 11-dione; C 18 H
12 O 3), which may be found in Salvia miltiorrhiza Bunge (Danshen), is a potent anti …
12 O 3), which may be found in Salvia miltiorrhiza Bunge (Danshen), is a potent anti …