Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity
Abstract Background Chlamydia trachomatis (Ct) is the most common infectious cause of
blindness and bacterial sexually transmitted infection worldwide. Ct strain-specific …
blindness and bacterial sexually transmitted infection worldwide. Ct strain-specific …
Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages
E Ghasemian, N Faal, H Pickering… - Microbial …, 2024 - microbiologyresearch.org
Trachoma, a neglected tropical disease caused by Chlamydia trachomatis (Ct) serovars A–
C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden …
C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden …
Whole-genome sequencing of ocular Chlamydia trachomatis isolates from Gadarif State, Sudan
Background Trachoma, caused by ocular Chlamydia trachomatis, is the leading infectious
cause of blindness worldwide. Sudan first reported trachoma in the 1930s and has since …
cause of blindness worldwide. Sudan first reported trachoma in the 1930s and has since …
Pathogenic Diversity among Chlamydia trachomatis Ocular Strains in Nonhuman Primates Is Affected by Subtle Genomic Variations
L Kari, WM Whitmire, JH Carlson… - The Journal of …, 2008 - academic.oup.com
Chlamydia trachomatis is the etiological agent of trachoma, the leading cause of
preventable blindness. Trachoma presents distinct clinical syndromes ranging from mild and …
preventable blindness. Trachoma presents distinct clinical syndromes ranging from mild and …
Genome-wide identification of Chlamydia trachomatis antigens associated with trachomatous trichiasis
C Lu, MJ Holland, S Gong, B Peng… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: Chlamydia trachomatis is the leading infectious cause of blindness. The goal of
the current study was to search for biomarkers associated with C. trachomatis–induced …
the current study was to search for biomarkers associated with C. trachomatis–induced …
Genomics of Ocular Chlamydia trachomatis After 5 Years of SAFE Interventions for Trachoma in Amhara, Ethiopia
H Pickering, A Chernet, E Sata… - The Journal of …, 2022 - academic.oup.com
Background To eliminate trachoma as a public health problem, the World Health
Organization recommends the SAFE (surgery, antibiotics, facial cleanliness, and …
Organization recommends the SAFE (surgery, antibiotics, facial cleanliness, and …
Chlamydia trachomatis ompA Variants in Trachoma: What Do They Tell Us?
AA Andreasen, MJ Burton, MJ Holland… - PLoS neglected …, 2008 - journals.plos.org
Background Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious
cause of blindness. Sequence-based analysis of the multiple strains typically present in …
cause of blindness. Sequence-based analysis of the multiple strains typically present in …
Unravelling Chlamydia trachomatis diversity in Amhara, Ethiopia: MLVA-ompA sequencing as a molecular typing tool for trachoma
AJ Harte, E Ghasemian, H Pickering… - PLOS Neglected …, 2024 - journals.plos.org
Trachoma is the leading infectious cause of blindness worldwide and is now largely
confined to around 40 low-and middle-income countries. It is caused by Chlamydia …
confined to around 40 low-and middle-income countries. It is caused by Chlamydia …
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study
CH Roberts, CS Franklin, P Makalo, H Joof, I Sarr… - Scientific reports, 2015 - nature.com
Chlamydia trachomatis causes both trachoma and sexually transmitted infections. These
diseases have similar pathology and potentially similar genetic predisposing factors. We …
diseases have similar pathology and potentially similar genetic predisposing factors. We …
Comparison of genovars and Chlamydia trachomatis infection loads in ocular samples from children in two distinct cohorts in Sudan and Morocco
Trachoma is a blinding disease caused by repeated conjunctival infection with different
Chlamydia trachomatis (Ct) genovars. Ct B genovars have been associated with more …
Chlamydia trachomatis (Ct) genovars. Ct B genovars have been associated with more …