Fixed Dose Combination Tablets of Aripiprazole and Divalproex Sodium: a Pilot Pharmacokinetic Study in Human Volunteers

Z Ahmed, F Subhan, S Ahmed - AAPS PharmSciTech, 2022 - Springer
A combination product of aripiprazole (antipsychotic) and divalproex sodium (mood
stabilizer) was recently developed to establish their tolerability and safety in fixed dose …

Development of fixed dose combination tablets of aripiprazole plus divalproex sodium and their simultaneous determination using HPLC-UV

Z Ahmed, F Subhan, S Ahmed… - Drug development …, 2016 - Taylor & Francis
A vast majority of psychiatric patients are effectively treated with combination of drugs to
improve efficacy and adherence, but due to limited research and development in fixed dose …

Comparative bioavailability of aripiprazole tablets and orally disintegrating tablets in young healthy volunteers

M Román, D Ochoa, A Rivas, C Belmonte… - Clinical Therapeutics, 2015 - Elsevier
Methods The study population included 167 healthy volunteers receiving 10 mg aripiprazole
in 6 single dose clinical trials (3 Abilify® tablets and 3 Abilify® ODT) under fasting …

Aripiprazole plasma concentrations delivered from two 2-month long-acting injectable formulations: an indirect comparison

M Harlin, C Chepke, F Larsen… - Neuropsychiatric …, 2023 - Taylor & Francis
Abstract Aripiprazole 2-month ready-to-use 960 mg (Ari 2MRTU 960) is a novel long-acting
injectable (LAI) formulation of aripiprazole monohydrate for administration once every 2 …

Bioequivalence of 2 aripiprazole orally disintegrating tablets in healthy Chinese volunteers under fasting and fed conditions

J Xiang, N Xu, X Wang, S Li, Q Yu… - Clinical …, 2021 - Wiley Online Library
To assess the bioequivalence of 2 formulations of aripiprazole orally disintegrating tablets
and to monitor their safety and tolerability in Chinese subjects, a single‐site, open‐label …

Pharmacokinetics of a new orally disintegrating tablet formulation of aripiprazole 15 mg administered without water in healthy middle-aged Korean subjects

Y Kim, JY Jeon, YC Chung, MG Kim - Clinical Therapeutics, 2015 - Elsevier
Purpose The main objective of this study was to compare the pharmacokinetic properties
and relative bioavailability of two 15-mg aripiprazole formulations (an orally disintegrating …

Effect of valproate on the plasma concentrations of aripiprazole in bipolar patients

G Eryilmaz, G Hizli Sayar, E Özten, IG Gül… - … Journal of Psychiatry …, 2014 - Taylor & Francis
Objective. There is very limited documentation available on the effects of valproate co-
medication on the pharmacokinetics of aripiprazole in a naturalistic setting. The aim of the …

[HTML][HTML] A phase-1 study comparing pharmacokinetic and safety profiles of three different dose intervals of aripiprazole lauroxil

R Risinger, M Hard, PJ Weiden - Psychopharmacology Bulletin, 2017 - ncbi.nlm.nih.gov
Background Aripiprazole lauroxil (AL) is an FDA-approved treatment for schizophrenia. AL is
a non-ester prodrug of aripiprazole that results in extended systemic release of aripiprazole …

Safety, efficacy, and patient acceptability of aripiprazole in the maintenance treatment of bipolar disorder

MP Rapagnani - Clinical Medicine Insights: Therapeutics, 2012 - journals.sagepub.com
Background Bipolar disorder (manic depression) is a serious, long-term mental illness that
affects about 1% of adults at some time during their life. It usually develops in late …

A sensitive column‐switching HPLC method for aripiprazole and dehydroaripiprazole and its application to human pharmacokinetic studies

Y Akamine, N Yasui‐Furukori, M Kojima… - Journal of separation …, 2010 - Wiley Online Library
A simple and sensitive column‐switching HPLC‐UV method was developed for the
simultaneous determination of aripiprazole, a novel atypical antipsychotic drug, and its …