Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …

Objectives:< p> Explain the etiology of ocular neuropathic pain.</p>< p> Review the
presentation of a patient with ocular neuropathic pain.</p>< p> Describe the current …

Importance Somatosensory dysfunction likely underlies dry eye (DE) symptoms in many
individuals yet remains an understudied component of the disease. Its presence has …

Background: Dysfunction at the ocular system via nociceptive or neuropathic mechanisms
can lead to chronic ocular pain. While many studies have reported on responses to …

Dysfunctional coping behaviors, such as catastrophizing, have been implicated in pain
severity and chronicity across several pain disorders. However, the impact of dysfunctional …

As the biological alarm of impending or actual tissue damage, pain is essential for our
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …

Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …

Purpose To investigate clinical characteristics of dry eye disease (DED) patients with a
chronic pain syndrome. Design Cross-sectional study. Methods Four hundred twenty-five …

Background/aims The frequent lack of association between dry eye (DE) symptoms and
signs leads to challenges in diagnosing and assessing the disease. Methods Participants …

Patients with corneal and conjunctival disorders report an array of ocular surface symptoms
including stinging, foreign body sensation, and itching. The intensity and perceptual quality …