Evidence that dry eye represents a chronic overlapping pain condition
Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …
[HTML][HTML] Ocular neuropathic pain
M Moshirfar, EE Benstead, PM Sorrentino, K Tripathy - 2019 - europepmc.org
Objectives:< p> Explain the etiology of ocular neuropathic pain.</p>< p> Review the
presentation of a patient with ocular neuropathic pain.</p>< p> Describe the current …
presentation of a patient with ocular neuropathic pain.</p>< p> Describe the current …
Assessment of somatosensory function in patients with idiopathic dry eye symptoms
Importance Somatosensory dysfunction likely underlies dry eye (DE) symptoms in many
individuals yet remains an understudied component of the disease. Its presence has …
individuals yet remains an understudied component of the disease. Its presence has …
Differential effects of treatment strategies in individuals with chronic ocular surface pain with a neuropathic component
Background: Dysfunction at the ocular system via nociceptive or neuropathic mechanisms
can lead to chronic ocular pain. While many studies have reported on responses to …
can lead to chronic ocular pain. While many studies have reported on responses to …
Dysfunctional coping mechanisms contribute to dry eye symptoms
Dysfunctional coping behaviors, such as catastrophizing, have been implicated in pain
severity and chronicity across several pain disorders. However, the impact of dysfunctional …
severity and chronicity across several pain disorders. However, the impact of dysfunctional …
Ocular neuropathic pain
P Rosenthal, D Borsook - British Journal of Ophthalmology, 2016 - bjo.bmj.com
As the biological alarm of impending or actual tissue damage, pain is essential for our
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …
Neuropathic corneal pain: approaches for management
G Dieckmann, S Goyal, P Hamrah - Ophthalmology, 2017 - Elsevier
Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …
Clinical characteristics of dry eye patients with chronic pain syndromes
J Vehof, NS Smitt-Kamminga, D Kozareva… - American journal of …, 2016 - Elsevier
Purpose To investigate clinical characteristics of dry eye disease (DED) patients with a
chronic pain syndrome. Design Cross-sectional study. Methods Four hundred twenty-five …
chronic pain syndrome. Design Cross-sectional study. Methods Four hundred twenty-five …
Epidemiology of discordance between symptoms and signs of dry eye
Background/aims The frequent lack of association between dry eye (DE) symptoms and
signs leads to challenges in diagnosing and assessing the disease. Methods Participants …
signs leads to challenges in diagnosing and assessing the disease. Methods Participants …
Pain, dryness, and itch sensations in eye surface disorders are defined by a balance between inflammation and sensory nerve injury
C Belmonte - Cornea, 2019 - journals.lww.com
Patients with corneal and conjunctival disorders report an array of ocular surface symptoms
including stinging, foreign body sensation, and itching. The intensity and perceptual quality …
including stinging, foreign body sensation, and itching. The intensity and perceptual quality …