Cardiac left ventricular (LV) remodeling is the final common pathway of most primary
cardiovascular diseases that manifest clinically as heart failure (HF). The more advanced the …

Left ventricular (LV) remodeling is a major determinant of the clinical course and outcome of
systolic heart failure (HF). Activation of neurohormonal and inflammatory cytokine pathways …

Abstract Heart failure (HF) affects 5.7 million Americans, costs $30.7 billion annually, and is
associated with a 50% 5-year mortality. The lifetime risk of HF in Americans is approximately …

Molecular imaging can detect and quantify pathophysiological processes underlying heart
failure, complementing evaluation of cardiac structure and function with other imaging …

Abstract Purpose of Review Cardiovascular diseases are the leading cause of deaths
worldwide. Many complex cellular and molecular pathways lead to myocardial remodeling …

Conclusions Noninvasive imaging of neurohumoral upregulation in remodeled myocardium
suggests that an imaging strategy can be developed for predicting the rate of remodeling …

Heart failure (HF), a heterogeneous syndrome of epidemic proportions, is increasingly
defined by its underlying molecular and genomic alterations. Molecular cardiac imaging has …

Adverse ventricular remodeling is believed to play a causative role in heart failure
progression and has a strong association with poor prognosis [1, 2]. The identification of …

Despite the many strides in the management of heart failure during the past 2 decades, the
efficacy of our current pharmacologic approach in heart failure is variable and is often …

The need for noninvasive assessment of cardiac volumes and ejection fraction (EF) ushered
in the use of cardiac imaging techniques in heart failure (HF) trials that investigated the roles …