Recent innovations in imaging techniques have provided key mechanistic insights into the
diverse phenotypic expressions of heart failure, with a wide range of potential applications to …

Myriad advances in all fields of cardiac imaging have stimulated and reflected new
understanding of cardiac performance, myocardial damage and the mechanisms of heart …

Chronic heart failure continues to impose a substantial health-care burden, despite recent
treatment advances. The key pathophysiological process that ultimately leads to chronic …

Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling,
Translational Therapies and Imaging Techniques provides an up-to-date introduction to the …

Left ventricular (LV) remodeling constitutes the final common pathway for the progression of
systolic dysfunction to end-stage heart failure (HF)[1, 2]. The renin–angiotensin system …

The key process leading to heart failure (HF) is cardiac remodelling in response to chronic
disease stresses. Several pathways, including those that regulate cardiomyocyte …

Heart failure is a multifaceted syndrome addressing for a high rate of death among the
general population. The common approach to this disease has been always based on the …

Purpose of review The prevalence of heart failure with preserved ejection fraction (HFpEF) is
rising and in some places, it is already the most prevalent form of heart failure. The usual …

The concept of ''cardiac remodeling''was first introduced in the 1970s to describe the
structural changes in left ventricular (LV) volume subsequent to a large myocardial …

Contemporary clinical trials in heart failure (HF) enroll patients largely based on acuity of
presentation, left ventricular ejection fraction (EF), and functional status. These trial …