BACKGROUND: Primary aldosteronism, characterized by overt renin-independent
aldosterone production, is a common but underrecognized form of hypertension and …

Background While both renin‐dependent and renin‐independent aldosterone secretion
contribute to aldosteronism, their relative associations with cardiovascular disease (CVD) …

A higher risk of cardiovascular events has been reported in patients with primary
aldosteronism (PA) than in otherwise similar patients with essential hypertension (EH) …

Objectives: To assess the prevalence of primary aldosteronism and its association with
cardiometabolic complications in patients with resistant and refractory hypertension …

Background: Aldosterone production and mineralocorticoid receptor activation are
implicated in myocardial fibrosis and cardiovascular events. Methods: Cardiac structure and …

Background: Primary aldosteronism is recognized as a severe form of renin-independent
aldosteronism that results in excessive mineralocorticoid receptor (MR) activation. Objective …

Primary aldosteronism, the most common secondary form of hypertension, is thought to be
present in≈ 5% to 10% of hypertensive adults. However, recent studies indicate that its …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …