[图书][B] Selenium compounds as a novel class of experimental cancer chemotherapeutics

AK Selvam - 2021 - search.proquest.com
Selenium is an essential micronutrient for humans, it has a narrow margin between
antioxidant and pro-oxidant effects. Redox-active selenium compounds have the potency to …

Therapeutic potential of selenium compounds in the treatment of cancer

AK Selvam, M Björnstedt, S Misra - Selenium, 2018 - Springer
The potential applications of different selenium compounds as cancer chemotherapeutic
agents is an active area of research within the field of cancer drug discovery. The …

Redox-active selenium compounds—From toxicity and cell death to cancer treatment

S Misra, M Boylan, A Selvam, JE Spallholz… - Nutrients, 2015 - mdpi.com
Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …

Selenite in cancer therapy

S Misra, M Wallenberg, O Brodin… - Diversity of selenium …, 2015 - books.google.com
Almost a century ago, the highly unique properties of selenium to inhibit the growth of
neoplastic cells and the great potential of selenium in the treatment of neoplasia were …

[HTML][HTML] Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment

V Gandin, P Khalkar, J Braude… - Free Radical Biology and …, 2018 - Elsevier
Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …

Understanding the redox biology of selenium in the search of targeted cancer therapies

JM Stolwijk, R Garje, JC Sieren, GR Buettner… - Antioxidants, 2020 - mdpi.com
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long
been suggested that selenium has anti-cancer properties. However, clinical trials have …

[HTML][HTML] Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: Preclinical and clinical development

Y Zakharia, A Bhattacharya, YM Rustum - Oncotarget, 2018 - ncbi.nlm.nih.gov
Selenium (Se)-containing molecules exert antioxidant properties and modulate targets
associated with tumor growth, metastasis, angiogenesis, and drug resistance. Prevention …

Selenium: roles in cancer prevention and therapies

X Geng, L Liu, KJ Tsai, Z Liu - Essential and Non-essential Metals …, 2017 - Springer
Selenium is an essential mineral for all animals including humans. It is found in amino acids
selenocysteine and selenomethionine, which usually forms active sites in selenoproteins. In …

Selenium cytotoxicity in cancer

M Wallenberg, S Misra… - Basic & clinical …, 2014 - Wiley Online Library
Selenium is an essential trace element with growth‐modulating properties. Decades of
research clearly demonstrate that selenium compounds inhibit the growth of malignant cells …

[PDF][PDF] Mono-Methyl Selenium and Cancer Therapy: Current Status and Future Translational Research Needs

K Barrow, C Jiang, J Lü - Biochem Pharmacol (Los Angel), 2015 - scholar.archive.org
The human clinical trials with seleno-methionine (SeMet) for prostate cancer prevention and
selenized-yeast (contains mostly SeMet) for the prevention of non-small cell lung cancer and …