Selenium compounds as novel potential anticancer agents

D Radomska, R Czarnomysy, D Radomski… - International Journal of …, 2021 - mdpi.com
The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …

Molecular mechanism behind the synergistic activity of diphenylmethyl selenocyanate and Cisplatin against murine tumor model

P Chakraborty, S Singha Roy… - Anti-Cancer Agents in …, 2015 - ingentaconnect.com
Various preclinical, clinical and epidemiological studies have already well established the
cancer chemopreventive and chemoprotective potential of selenium compounds. In addition …

Organoselenium compounds as cancer therapeutic agents

V Gandin, AP Fernandes - 2017 - books.rsc.org
During recent decades, the connection between selenium and cancer has been studied
widely and from many different aspects, ranging from the use as a trace element to a cancer …

[图书][B] Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments

VK Jain, KI Priyadarsini - 2017 - books.google.com
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This
book discusses organoselenium chemistry and biology in the context of its therapeutic …

Selenium action in neuro-oncology

E Yakubov, M Buchfelder, IY Eyüpoglu… - Biological trace element …, 2014 - Springer
The trace element selenium and selenocysteine-carrying selenoproteins play a pivotal role
in the brain. Beside the essential function during development and maintenance of brain …

Aspects of a distinct cytotoxicity of selenium salts and organic selenides in living cells with possible implications for drug design

E Castellucci Estevam, K Witek, L Faulstich, MJ Nasim… - Molecules, 2015 - mdpi.com
Selenium is traditionally considered as an antioxidant element and selenium compounds
are often discussed in the context of chemoprevention and therapy. Recent studies …

New concepts in selenium chemoprevention

C Ip, Y Dong, HE Ganther - Cancer and Metastasis Reviews, 2002 - Springer
This article highlights some recent advances in selenium cancer chemoprevention research.
It has been well documented that the chemical transformation of selenium to a …

Cancer chemoprevention: selenium as a prooxidant, not an antioxidant

EN Drake - Medical hypotheses, 2006 - Elsevier
Although the average daily dietary selenium (Se) intake in the United States is consistently
above the adult RDA of 55μg Se/day, supranutritional supplements of 200μg Se/day have …

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cells

T Chen, YS Wong - Biomedicine & Pharmacotherapy, 2009 - Elsevier
Epidemiological and clinical studies have demonstrated that dietary supplementation of
selenium (Se) could reduce the incidence of human cancers. In this study, selenocystine, a …

Selenium and cancer stem cells

G Murdolo, D Bartolini, C Tortoioli, M Piroddi… - Advances in Cancer …, 2017 - Elsevier
Selenium (Se) is an essential micronutrient that functions as “redox gatekeeper” and
homeostasis factor of normal and cancer cells. Epidemiology and experimental studies, in …