Selenium-based drug design: rationale and therapeutic potential
SW May - Expert Opinion on Investigational Drugs, 1999 - Taylor & Francis
The wide media coverage given recently to a study correlating higher selenium levels with a
reduced risk of advanced prostate cancer is but the latest addition to a growing body of …
reduced risk of advanced prostate cancer is but the latest addition to a growing body of …
Selenium as a Modulator of Efficacy and Toxicity of Chemotherapy and Radiation
R Lobb - 2011 - researchcommons.waikato.ac.nz
Selenium (Se) is an essential trace mineral required in maintaining health in humans.
Recent research has demonstrated that Se shows promise as an agent that can reduce the …
Recent research has demonstrated that Se shows promise as an agent that can reduce the …
Selenium-Containing Agents Acting on Cancer—A New Hope?
S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
Selenium-containing agents are more and more considered as an innovative potential
treatment option for cancer. Light is shed not only on the considerable advancements made …
treatment option for cancer. Light is shed not only on the considerable advancements made …
In Vitro and in Vivo Studies of Methylseleninic Acid: Evidence That a Monomethylated Selenium Metabolite Is Critical for Cancer Chemoprevention
C Ip, HJ Thompson, Z Zhu, HE Ganther - Cancer research, 2000 - AACR
Previous research suggested that the β-lyase-mediated production of a monomethylated
selenium metabolite from Se-methylselenocysteine is a key step in cancer chemoprevention …
selenium metabolite from Se-methylselenocysteine is a key step in cancer chemoprevention …
Differential effects of selenium (Se) on normal and malignant cells treated with chemotherapy (CT) and radiation (RT).
e13583 Background: Preclinical work has demonstrated that Se compounds potentiate
anticancer effects of CT and RT while reducing normal tissue toxicities. The molecular basis …
anticancer effects of CT and RT while reducing normal tissue toxicities. The molecular basis …
Selenium as a cancer preventative and therapeutic agent: defining mechanisms of action and optimal doses
O Al Assaad - 2023 - openresearch.surrey.ac.uk
Abstract< b> Background</b> Selenium (Se) is an essential micronutrient that may exert
cancer-selective cytotoxicity at supranutritional exposures. It has been proposed Se exerts …
cancer-selective cytotoxicity at supranutritional exposures. It has been proposed Se exerts …
[引用][C] Selenium and Cancer Prevention
C IP, J MARSHALL, YMEE PARK, H ZHANG… - Nutritional …, 2006 - Elsevier
Apoptotic cellular events for selenium compounds involved in cancer prevention
H Rikiishi - Journal of bioenergetics and biomembranes, 2007 - Springer
Converging data from epidemiological, ecological, and clinical studies have shown that
selenium (Se) can decrease the risk for some types of human cancers. Induction of …
selenium (Se) can decrease the risk for some types of human cancers. Induction of …
Reactive selenium species: Redox modulation, antioxidant, antimicrobial and anticancer activities
Since its discovery 200 years ago, in 1817, by Jöns Jacob Berzelius (1779–1848), the
element selenium has had a rather chequered relationship with biology and medicine, an …
element selenium has had a rather chequered relationship with biology and medicine, an …