Simple Summary Alcoholic beverages and acetaldehyde formed during their metabolism
are carcinogenic to humans. Alcohol drinking may affect bone marrow stem cell niche …

Ethanol (EtOH) is a recreationally ingested compound that is both teratogenic and
carcinogenic in humans. Because of its abundant consumption worldwide and the vital role …

The gradual acquisition of mutations in the genome of somatic cells is a hallmark of aging
and leads to the evolution of a range of age-associated diseases, such as cancer. The …

Simple Summary Of all yearly deaths attributable to alcohol consumption globally,
approximately 12% are due to cancers, representing approximately 0.4 million deceased …

The purpose of this review is to briefly summarize the roles of alcohol (ethanol) and related
compounds in promoting cancer and inflammatory injury in many tissues. Long-term chronic …

Alcohol is eliminated from the body by various metabolic mechanisms. The primary enzymes
in such mechanism involved are alcohol dehydrogenase, aldehyde dehydrogenase …

Hematopoiesis involves the orderly production of millions of blood cells per second from a
small number of essential bone marrow cells termed hematopoietic stem cells (HSCs) …

As described in Chap. 1, alcohol has been classified as carcinogenic to humans at several
sites in the body by the International Agency for Research on Cancer (Secretan et al. 2009) …

Excessive consumption of alcohol is a leading cause of lifestyle-induced morbidity and
mortality worldwide. Although long-term alcohol abuse has been shown to be detrimental to …

We discuss evidence indicating how ethanol could generate oxygen free radicals. Recent
use of techniques such as spin trapping and EPR spectroscopy have demonstrably …