ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations

VS Hernández, MA Zetter, EC Guerra… - Experimental …, 2021 - Elsevier
We examined cell type-specific expression and distribution of rat brain angiotensin-
converting enzyme 2 (ACE2), the receptor for SARS-CoV-2, in the rodent brain. ACE2 is …

Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping

Y Zhang, SR Archie, Y Ghanwatkar, S Sharma… - Fluids and Barriers of …, 2022 - Springer
Background Knowledge of the entry receptors responsible for SARS-CoV-2 is key to
understand the neural transmission and pathogenesis of COVID-19 characterized by a …

SARS-CoV-2 infectivity and neurological targets in the brain

WJ Lukiw, A Pogue, JM Hill - Cellular and molecular neurobiology, 2022 - Springer
The gateway for invasion by the novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) into human host cells is via the angiotensin-converting enzyme 2 (ACE2) …

[HTML][HTML] Angiotensin converting enzyme 2 (ACE2) expression in the aged brain and visual system

JM Hill, C Clement, L Arceneaux… - Journal of aging …, 2021 - ncbi.nlm.nih.gov
Multiple lines of evidence currently indicate that the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) gains entry into human host cells via a high-affinity interaction …

The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in the human and mouse brains

R Chen, K Wang, J Yu, D Howard, L French… - Frontiers in …, 2021 - frontiersin.org
By engaging angiotensin-converting enzyme 2 (ACE2 or Ace2), the novel pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells and …

Altered COVID-19 receptor ACE2 expression in a higher risk group for cerebrovascular disease and ischemic stroke

JY Choi, HK Lee, JH Park, SJ Cho, M Kwon… - Biochemical and …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a worldwide pandemic. It has a high
transmission rate among humans, and is a threat to global public health. However, there are …

Neurological manifestations of coronavirus infections: role of angiotensin-converting enzyme 2 in COVID-19

N Parsamanesh, A Pezeshgi, M Hemmati… - International Journal …, 2022 - Taylor & Francis
Aim of the study In December 2019, a highly pathogenic coronavirus called SARS-CoV-2
(formerly identified as 2019-nCoV) appeared in Wuhan, China, and has since been …

The altered anatomical distribution of ACE2 in the brain with Alzheimer's disease pathology

H Cui, S Su, Y Cao, C Ma, W Qiu - Frontiers in Cell and …, 2021 - frontiersin.org
The whole world is suffering from the coronavirus disease 2019 (COVID-19) pandemic,
induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through …

ACE2, Circumventricular Organs and the Hypothalamus, and COVID-19

WY Ong, RL Satish, DR Herr - NeuroMolecular Medicine, 2022 - Springer
The SARS-CoV-2 virus gains entry to cells by binding to angiotensin-converting enzyme 2
(ACE2). Since circumventricular organs and parts of the hypothalamus lack a blood–brain …

Protein expression profile of ACE2 in the normal and COVID-19-affected human brain

C Lindskog, L Méar, J Virhammar… - Journal of Proteome …, 2022 - ACS Publications
SARS-coronavirus 2 (SARS-CoV-2) that caused the coronavirus disease 2019 (COVID-19)
pandemic has posed to be a global challenge. An increasing number of neurological …