Granulocyte colony‐stimulating factor and its potential application for skeletal muscle repair and regeneration
Granulocyte colony‐stimulating factor (G‐CSF) was originally discovered in the context of
hematopoiesis. However, the identification of the G‐CSF receptor (G‐CSFR) being …
hematopoiesis. However, the identification of the G‐CSF receptor (G‐CSFR) being …
Regulation of granulocyte colony-stimulating factor and its receptor in skeletal muscle is dependent upon the type of inflammatory stimulus
CR Wright, EL Brown, PA Della Gatta… - Journal of Interferon & …, 2015 - liebertpub.com
The cytokine granulocyte colony-stimulating factor (G-CSF) binds to its receptor (G-CSFR) to
stimulate hematopoietic stem cell mobilization, myelopoiesis, and the production and …
stimulate hematopoietic stem cell mobilization, myelopoiesis, and the production and …
[HTML][HTML] G-CSF does not influence C2C12 myogenesis despite receptor expression in healthy and dystrophic skeletal muscle
Granulocyte-colony stimulating factor (G-CSF) increases recovery of rodent skeletal muscles
after injury, and increases muscle function in rodent models of neuromuscular disease …
after injury, and increases muscle function in rodent models of neuromuscular disease …
Granulocyte-colony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in rats
I Stratos, R Rotter, C Eipel… - Journal of Applied …, 2007 - journals.physiology.org
Insufficiency of skeletal muscle regeneration often impedes the healing process with
functional deficiencies and scar formation. We tested the hematopoietic growth factor …
functional deficiencies and scar formation. We tested the hematopoietic growth factor …
G-CSF influences mouse skeletal muscle development and regeneration by stimulating myoblast proliferation
M Hara, S Yuasa, K Shimoji, T Onizuka… - Journal of Experimental …, 2011 - rupress.org
After skeletal muscle injury, neutrophils, monocytes, and macrophages infiltrate the
damaged area; this is followed by rapid proliferation of myoblasts derived from muscle stem …
damaged area; this is followed by rapid proliferation of myoblasts derived from muscle stem …
Critical role for granulocyte colony-stimulating factor in inflammatory arthritis
KE Lawlor, IK Campbell, D Metcalf… - Proceedings of the …, 2004 - National Acad Sciences
Granulocyte colony-stimulating factor (G-CSF) is a well known regulator of granulopoiesis,
but the role of endogenous G-CSF in inflammatory joint disease has not been explored. We …
but the role of endogenous G-CSF in inflammatory joint disease has not been explored. We …
Targeting GM-CSF in inflammatory diseases
IP Wicks, AW Roberts - Nature Reviews Rheumatology, 2016 - nature.com
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth factor first
identified as an inducer of differentiation and proliferation of granulocytes and macrophages …
identified as an inducer of differentiation and proliferation of granulocytes and macrophages …
G-CSF: function and modes of action
S Basu, A Dunn, A Ward - International journal of …, 2002 - spandidos-publications.com
Since the observations in the 1960s that granulocyte-colony stimulating factor (G-CSF)
stimulated the proliferation of granulocytic cells in semisolid cultures of bone marrow cells, G …
stimulated the proliferation of granulocytic cells in semisolid cultures of bone marrow cells, G …
Targeting GM-CSF in inflammatory and autoimmune disorders
AA Achuthan, KMC Lee, JA Hamilton - Seminars in immunology, 2021 - Elsevier
Granulocyte macrophage-colony stimulating factor (GM-CSF) was originally identified as a
growth factor for its ability to promote the proliferation and differentiation in vitro of bone …
growth factor for its ability to promote the proliferation and differentiation in vitro of bone …
[HTML][HTML] GM-CSF in inflammation
JA Hamilton - Journal of Experimental Medicine, 2020 - rupress.org
Granulocyte–macrophage colony-stimulating factor (GM-CSF) has many more functions
than its original in vitro identification as an inducer of granulocyte and macrophage …
than its original in vitro identification as an inducer of granulocyte and macrophage …