Results: At baseline, dyslipidemia in both groups was characterized by increased serum
levels of total cholesterol and low density lipoprotein cholesterol (LDL-C). Serum high …

Background—Macrophages play a central role in the development of atherosclerosis.
However, the signaling pathways that regulate their function are not well understood. The …

Accumulating evidence suggests that Rho-associated kinase (ROCK) may be important in
the pathogenesis of atherosclerosis and coronary vasospasm. In the present study, we …

Objective—Cardiovascular diseases are associated with chronic activation of Rho-
associated kinases (ROCKs) and endothelial dysfunction. Both increased ROCK activity and …

Rho-associated kinases (ROCKs) have been shown to be involved in the pathogenesis of
atherosclerosis. Although smoking is associated with endothelial dysfunction and ROCK …

Background: Few clinical studies have assessed Rho kinase (ROCK) in patients with
diabetes mellitus (DM) and ST-segment elevation myocardial infarction (STEMI). This study …

Objectives: We sought to determine whether Rho kinase (ROCK) activity is increased in a
Taiwanese population with metabolic syndrome (MetS). Background: Recent studies …

Background: Obesity is a chronic low-grade inflammatory state that is related to prediabetes,
increased Rhoassociated kinase 2 (ROCK2) activity and concentration of high-sensitivity C …

Background The intracellular ROCK signaling pathway is an important modulator of blood
pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased …

Introduction: Coronary artery disease (CAD) is an ischemic condition that occurs as a result
of partial or complete interruption of blood flow by narrowing or complete blockage of the …