Recent genome-wide association studies (GWAS) of Hodgkin lymphoma (HL) have
identified associations with genetic variation at both HLA and non-HLA loci; however, much …

Several genetic and environmental factors are reported to be involved in the predisposing or
prevention of hematologic malignancies. Due to their high polymorphisms, human …

Familial aggregation of Hodgkin lymphoma (HL) has been demonstrated in large population
studies, pointing to genetic predisposition to this hematological malignancy. To understand …

Human leukocyte antigen (HLA) gene variation is associated with risk of cancers,
particularly those with infectious etiology or hematopoietic origin, given its role in immune …

Background In Caucasian populations, the tumor cells of Epstein Barr virus (EBV)-positive
classical Hodgkin Lymphomas (cHL) patients more frequently express HLA class I and HLA …

METHODS Ascertainment of HL pedigrees The Genetic Epidemiology Branch (Division of
Cancer Epidemiology and Genetics) has been recruiting families with two or more living …

Through a literature search, we identified a total of 59 nuclear families with Hodgkin's
disease (HD). The affected individuals in these families were HLA haplotyped. To evaluate …

Familial lymphoma is relatively rare. Therefore, its precise incidence in the general
population remains elusive. Haim et al.(19) evaluated the statistical significance of familial …

ABSTRACT Background: Non-Hodgkin lymphoma (NHL) is a major cancer in Egypt and
worldwide and has many risk factors including genes involved in the immune response. Aim …

To identify genes involved in the pathogenesis of classical Hodgkin lymphoma (cHL), we
performed serial analysis of gene expression (SAGE) and array‐based comparative …