The NMDA receptor is a glutamatergic ionotropic receptor key in mediating neuronal
plasticity across virtually all synaptic circuits in the brain. An increasing list of neurological …

NMDA receptors mediate excitatory synaptic transmission and regulate synaptic plasticity in
the central nervous system, but their dysregulation is also implicated in numerous brain …

The N-methyl-d-aspartate receptor plays a critical role in central nervous system processes.
Its diverse properties, as well as hypothesized role in neurological disease, render NMDA …

The N-methyl-d-aspartate receptor (NMDAR) is a Na+ and Ca2+ permeable ionotropic
glutamate receptor that is activated by the coagonists glycine and glutamate. NMDARs are …

The NMDA receptor (NMDAR) family of l-glutamate receptors are well known to have
diverse roles in CNS function as well as in various neuropathological and psychiatric …

NMDA receptors are glutamate-activated ion-channels involved in many essential brain
functions including learning, memory, cognition, and behavior. Given this broad range of …

NMDA receptors (NMDARs) contribute to several neuropathological processes. Novel
positive allosteric modulators (PAMs) of NMDARs have recently been identified but their …

NMDA Receptors (NMDARs) play key roles in synaptic physiology and NMDAR
hypofunction has been implicated in various neurological conditions. In recent years an …

N-methyl-d-aspartate receptors (NMDARs) are glutamate-gated ion channels that play key
roles in brain physiology and pathology. Because numerous pathologic conditions involve …

Highlights•NMDA receptors form massive multi-domain multi-subunit molecular
complexes.•NMDA receptors harbor a multiplicity of binding sites for allosteric modulators.•N …